Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3493236 | 0.82 | HPGDS (0.60) | RAB9AHPGDSLMNAMEN1KMT2A | |
| SCHEMBL27321802 | 0.72 | RAB9A (0.63) | RAB9AHPGDSLMNAALDH1A1HPGD | |
| SCHEMBL3491623 | 0.72 | RAB9A (0.50) | RAB9ALMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL1753182 | 0.71 | HPGDS (0.60) | RAB9AHPGDSLMNAALDH1A1HPGD | |
| SCHEMBL10172532 | 0.71 | HPGDS (0.60) | RAB9AHPGDSLMNAALDH1A1HPGD | |
| SCHEMBL11351745 | 0.70 | ALDH1A1 (0.58) | RAB9AHPGDSLMNAMEN1KMT2A | |
| SCHEMBL509233 | 0.69 | LMNA (0.55) | HPGDSLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL5330670 | 0.68 | HPGDS (0.56) | RAB9AHPGDSLMNAALDH1A1HPGD | |
| SCHEMBL31361376 | 0.68 | HPGDS (0.50) | RAB9AHPGDSLMNAMEN1KMT2A | |
| SCHEMBL16154002 | 0.68 | LMNA (0.60) | RAB9ALMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999232-A | MAT2A inhibitors | 南京正大天晴制药有限公司 | 2022-02-01 | — | — | CN | disclosed |