Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 6/20 | 0.57 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.48 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.48 |
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28654035 | 0.79 | ALDH1A1 (0.77) | GRIN1GRIN2BALDH1A1TAOK1TAOK3 | |
| SCHEMBL28655102 | 0.79 | GRIN1 (0.65) | GRIN1GRIN2BALDH1A1GBA1KDM4E | |
| SCHEMBL22669039 | 0.78 | TAOK1 (0.62) | GRIN1GRIN2BALDH1A1TAOK1TAOK3 | |
| SCHEMBL28655075 | 0.78 | ALDH1A1 (0.59) | GRIN1GRIN2BALDH1A1TAOK1TAOK3 | |
| SCHEMBL28668119 | 0.78 | ALDH1A1 (0.59) | GRIN1GRIN2BALDH1A1TAOK1TAOK3 | |
| SCHEMBL25811671 | 0.78 | ALDH1A1 (0.63) | GRIN1GRIN2BALDH1A1TAOK1TAOK3 | |
| SCHEMBL28650418 | 0.78 | GBA1 (0.56) | GRIN1GRIN2BALDH1A1TAOK1TAOK3 | |
| SCHEMBL19555741 | 0.78 | ALDH1A1 (0.59) | GRIN1GRIN2BALDH1A1GBA1KDM4E | |
| SCHEMBL28649848 | 0.77 | OGG1 (0.58) | GRIN1GRIN2BALDH1A1ADAMTS5KDM4E | |
| SCHEMBL28668110 | 0.76 | ALDH1A1 (0.60) | GRIN1GRIN2BALDH1A1GBA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113692276-A | NURR1 receptor modulators | 加利福尼亚大学董事会 | 2021-11-23 | — | — | CN | disclosed |