SCHEMBL28675586

SCHEMBL28675586

Cc1cc(C)c(O)c(Cc2cc(C3CCCCC3)c(O)cc2C)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 3/20 0.40
CYP2C19 P33261 3/20 0.40
CYP2D6 P10635 2/20 0.40
HIF1A Q16665 2/20 0.40
HSD17B10 Q99714 1/20 0.40
AMY1A P0DUB6 1/20 0.39
PSMB5 P28074 1/20 0.38
NUDT1 P36639 1/20 0.36
BACE1 P56817 1/20 0.36
CYP1A2 P05177 1/20 0.36
HSPA5 P11021 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
SLC5A1 P13866 2/20 0.34
SLC5A2 P31639 2/20 0.34
SHBG P04278 1/20 0.33
HSP90AA1 P07900 1/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.33
TAS1R3 Q7RTX0 2/20 0.32
TAS1R1 Q7RTX1 2/20 0.32
TAS1R2 Q8TE23 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL278212 0.89 NUDT1 (0.43) CYP2D6PSMB5NUDT1BACE1CYP1A2
SCHEMBL30677888 0.89 NUDT1 (0.43) CYP2D6PSMB5NUDT1BACE1CYP1A2
SCHEMBL278225 0.88 SHBG (0.49) CYP2C9CYP2C19CYP2D6HIF1AHSD17B10
SCHEMBL23174721 0.80 NUDT1 (0.38) NUDT1BACE1SLC5A1SLC5A2HSP90AA1
SCHEMBL28676321 0.80 NUDT1 (0.40) NUDT1BACE1SLC5A1SLC5A2HSP90AA1
SCHEMBL27560096 0.80 HSPA5 (0.44) NUDT1BACE1HSPA5SMN1; SMN2SLC5A1
SCHEMBL5485645 0.79 NUDT1 (0.46) CYP2C9CYP2C19CYP2D6PSMB5NUDT1
SCHEMBL34995 0.79 AMY1A (0.43) CYP2C9CYP2C19CYP2D6HIF1AHSD17B10
SCHEMBL29556326 0.79 AMY1A (0.43) CYP2C9CYP2C19CYP2D6HIF1AHSD17B10
SCHEMBL29381510 0.79 AMY1A (0.43) CYP2C9CYP2C19CYP2D6HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113785023-B Water-based ink composition for reversible thermochromic writing instrument, refill for refill and water-based ballpoint pen incorporating same 株式会社百乐 2023-05-12 CN disclosed
CN-113785023-A Water-based ink composition for reversible thermal discoloration writing instrument, refill containing the same, and water-based ballpoint pen 株式会社百乐 2021-12-10 CN disclosed