SCHEMBL28675670

SCHEMBL28675670

Oc1cccc(OB(Oc2cccc(O)c2)c2ccccc2)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 2/20 0.45
CYP3A4 P08684 3/20 0.43
CA12 O43570 2/20 0.41
CA2 P00918 2/20 0.41
CA9 Q16790 2/20 0.41
CA14 Q9ULX7 2/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
CA5A P35218 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CA5B Q9Y2D0 1/20 0.41
DRD2 P14416 1/20 0.41
DRD4 P21917 1/20 0.41
ADRA1D P25100 1/20 0.41
ADRA1A P35348 1/20 0.41
ADRA1B P35368 1/20 0.41
DRD3 P35462 1/20 0.41
APP P05067 1/20 0.39
CHRNB2 P17787 1/20 0.39
CHRNA4 P43681 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6379719 0.83 ENPP2 (0.48) ENPP2CYP3A4CA12CA2CA9
SCHEMBL29028912 0.80 CYP3A4 (0.46) ENPP2CYP3A4CA12CA2CA9
SCHEMBL734634 0.79 CA4 (0.46) ENPP2CYP3A4CA2CA9CA14
SCHEMBL25213274 0.77 CYP3A4 (0.50) ENPP2CYP3A4CA12CA2CA9
SCHEMBL6610175 0.77 ACHE (0.50) ALDH1A1LMNADRD2DRD4TSHR
SCHEMBL1302549 0.75 CYP3A4 (0.48) ENPP2CYP3A4CA12CA2CA9
SCHEMBL450261 0.73 LTA4H (0.62) CYP3A4CA12CA2CA9CA14
SCHEMBL2859448 0.73 CYP3A4 (0.50) ENPP2CYP3A4CA12CA2CA9
Hydroquinone SCHEMBL9791308 0.72 CYP3A4 (0.46) ENPP2CYP3A4CA12CA2CA9
SCHEMBL5841559 0.72 ACHE (0.44) ALDH1A1LMNADRD2DRD4DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113968878-A Hyperbranched boric acid modified phthalonitrile monomer and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2022-01-25 CN disclosed