Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | SREBF2 | Q12772 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 4/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19626741 | 0.81 | GAA (0.54) | LMNAMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL3129405 | 0.81 | LTA4H (0.64) | LMNAMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL19625297 | 0.78 | LMNA (0.44) | LMNAMEN1KMT2ASMN1; SMN2SREBF2 | |
| SCHEMBL8515140 | 0.76 | LTA4H (0.68) | LMNAMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL3173201 | 0.73 | ALOX5 (0.63) | LMNAMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL20504926 | 0.73 | RAB9A (0.61) | LMNAMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL28728351 | 0.73 | RAB9A (0.56) | LMNAMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL19006692 | 0.73 | LTA4H (0.48) | LMNAMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL11491535 | 0.73 | LTA4H (0.58) | LMNAMEN1KMT2ASMN1; SMN2SREBF2 | |
| SCHEMBL3761557 | 0.72 | ALDH1A1 (0.61) | LMNAMEN1KMT2ASMN1; SMN2SREBF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776537-B | Purine diones as WNT pathway modulators | 新加坡科技研究局 | 2021-12-14 | — | — | CN | disclosed |