Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TEK | Q02763 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30023283 | 1.00 | KDM4E (0.45) | KDM4EALDH1A1POLBHPGDTEK | |
| SCHEMBL30023247 | 1.00 | KDM4E (0.45) | KDM4EALDH1A1POLBHPGDTEK | |
| SCHEMBL28680766 | 1.00 | KDM4E (0.45) | KDM4EALDH1A1POLBHPGDTEK | |
| SCHEMBL30022887 | 0.94 | ALDH1A1 (0.50) | KDM4EALDH1A1POLBHPGDGPR35 | |
| SCHEMBL19929844 | 0.88 | ALDH1A1 (0.46) | KDM4EALDH1A1POLBHPGDGPR35 | |
| SCHEMBL30023352 | 0.81 | RXRA (0.38) | KDM4EALDH1A1POLBHPGDGPR35 | |
| SCHEMBL28668413 | 0.81 | MEN1 (0.47) | KDM4EALDH1A1HPGDADORA3NPC1 | |
| SCHEMBL30020913 | 0.81 | MAPT (0.48) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL28654875 | 0.80 | KDM4E (0.50) | KDM4EALDH1A1POLBHPGDGPR35 | |
| SCHEMBL30022955 | 0.80 | KDM4E (0.50) | KDM4EALDH1A1POLBHPGDGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754619-B | Method for preparing polysubstituted benzofuran-4-formic acid compound under catalysis of ruthenium | 广州大学 | 2022-12-20 | — | — | CN | disclosed |
| CN-113754619-A | Method for preparing polysubstituted benzofuran-4-formic acid compound under catalysis of ruthenium | 广州大学 | 2021-12-07 | — | — | CN | disclosed |