Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 1.00 |
| ▸ | NPC1 | O15118 | 2/20 | 1.00 |
| ▸ | RAB9A | P51151 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 7/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.78 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.78 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 4/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MPI | P34949 | 1/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12167638 | 0.84 | RAB9A (0.72) | SMN1; SMN2L3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL14112022 | 0.82 | L3MBTL1 (0.69) | SMN1; SMN2L3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL4619352 | 0.82 | NPC1 (0.70) | SMN1; SMN2L3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL28678208 | 0.82 | MAPT (1.00) | SMN1; SMN2L3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL9871210 | 0.82 | RAB9A (0.69) | SMN1; SMN2L3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL4639142 | 0.82 | SCN9A (0.70) | SMN1; SMN2L3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL45506 | 0.81 | MAPT (0.68) | SMN1; SMN2L3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL7360935 | 0.81 | HSP90AA1 (1.00) | SMN1; SMN2L3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL12003962 | 0.80 | MEN1 (0.80) | SMN1; SMN2L3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL4619283 | 0.79 | L3MBTL1 (0.65) | SMN1; SMN2L3MBTL1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869958-A1 | NOVEL INDOLE-2,3-DIONE-3-OXIME DERIVATIVES | NEUROSEARCH A/S (DK) | 1998-10-14 | — | — | EP | claimed |
| WO-1998014447-A1 | NOVEL INDOLE-2,3-DIONE-3-OXIME DERIVATIVES | NEUROSEARCH A/S (DK) | 1998-04-09 | — | — | WO | claimed |