Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.69 |
| ▸ | NPC1 | O15118 | 3/20 | 0.69 |
| ▸ | RAB9A | P51151 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 6/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | POLB | P06746 | 3/20 | 0.66 |
| ▸ | BLM | P54132 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.58 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MPI | P34949 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628518 | 0.82 | SMN1; SMN2 (1.00) | SCN9AL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28678208 | 0.80 | MAPT (1.00) | L3MBTL1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8871046 | 0.78 | MAPT (0.67) | L3MBTL1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL4619352 | 0.78 | NPC1 (0.70) | SCN9AL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4619288 | 0.77 | MAPT (0.60) | SCN9AL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8625603 | 0.77 | MAPT (0.62) | L3MBTL1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL5227497 | 0.76 | CYP3A4 (0.72) | SCN9ASMN1; SMN2ALDH1A1BLMMEN1 | |
| SCHEMBL9284192 | 0.76 | MAPT (0.68) | L3MBTL1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL45506 | 0.76 | MAPT (0.68) | L3MBTL1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL15818384 | 0.76 | MAPT (0.60) | L3MBTL1NPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080166310-A1 | Administration of 2-oxyacetamide compounds for promoting and/or inducing and/or stimulating the pigmentation of keratin materials and/or for limiting the depigmentation and/or bleaching thereof | L'OREAL (FR) | 2008-07-10 | — | — | US | disclosed |
| US-20080166310-A1 | Administration of 2-oxyacetamide compounds for promoting and/or inducing and/or stimulating the pigmentation of keratin materials and/or for limiting the depigmentation and/or bleaching thereof | L'OREAL (FR) | 2008-07-10 | — | — | US | disclosed |
| US-20080166310-A1 | Administration of 2-oxyacetamide compounds for promoting and/or inducing and/or stimulating the pigmentation of keratin materials and/or for limiting the depigmentation and/or bleaching thereof | L'OREAL (FR) | 2008-07-10 | — | — | US | disclosed |
| EP-1888017-A1 | USE OF-OXYACETAMIDE COMPOUNDS FOR PROMOTING AND/OR INDUCING AND/OR STIMULATING THE PIGMENTATION OF KERATIN MATERIALS AND/OR FOR LIMITING THEIR DEPIGMENTATION AND/OR BLEACHING | L'Oréal (FR) | 2008-02-20 | — | — | EP | disclosed |
| US-20070092467-A1 | Oxyacetamide compounds useful for stimulating or inducing the growth and/or retarding the loss of keratin fibers | L'OREAL (FR) | 2007-04-26 | — | — | US | disclosed |
| US-20070092467-A1 | Oxyacetamide compounds useful for stimulating or inducing the growth and/or retarding the loss of keratin fibers | L'OREAL (FR) | 2007-04-26 | — | — | US | disclosed |
| US-20070092467-A1 | Oxyacetamide compounds useful for stimulating or inducing the growth and/or retarding the loss of keratin fibers | L'OREAL (FR) | 2007-04-26 | — | — | US | disclosed |
| EP-1763382-A1 | 2-OXY-ACETAMIDE COMPOUND, THE USES THEREOF AND COMPOSITIONS FOR STIMULATING OR INDUCING THE GROWTH, AND/OR RETARDING THE LOSS, OF KERATIN FIBRES | L'OREAL (FR) | 2007-03-21 | — | — | EP | disclosed |
| WO-2006131282-A1 | USE OF-OXYACETAMIDE COMPOUNDS FOR PROMOTING AND/OR INDUCING AND/OR STIMULATING THE PIGMENTATION OF KERATIN MATERIALS AND/OR FOR LIMITING THEIR DEPIGMENTATION AND/OR BLEACHING | L'ORÉAL (FR) | 2006-12-14 | — | — | WO | disclosed |
| WO-2005107687-A1 | 2-OXY-ACETAMIDE COMPOUND, THE USES THEREOF AND COMPOSITIONS FOR STIMULATING OR INDUCING THE GROWTH, AND/OR RETARDING THE LOSS, OF KERATIN FIBRES | L'OREAL (FR) | 2005-11-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070092467-A1 | Oxyacetamide compounds useful for stimulating or inducing the growth and/or retarding the loss of keratin fibers | HPGD, KRT18, PTGS1 | SCN9A 2115/4885L3MBTL1 4657/4885NPC1 4052/4885 |
| US-20080166310-A1 | Administration of 2-oxyacetamide compounds for promoting and/or inducing and/or stimulating the pigmentation of keratin materials and/or for limiting the depigmentation and/or bleaching thereof | KRT18, TYR, CRYAA | SCN9A 434/4885L3MBTL1 3737/4885NPC1 4047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.