Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | PBK | Q96KB5 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287365 | 0.89 | NPY5R (0.41) | ALDH1A1MAPTNPY5RHPGDPBK | |
| SCHEMBL287828 | 0.85 | ALDH1A1 (0.38) | ALDH1A1HPGDPBKERCC5FEN1 | |
| SCHEMBL286982 | 0.76 | KMT2A (0.41) | ALDH1A1MAPTNPSR1 | |
| SCHEMBL286788 | 0.72 | MAPT (0.35) | ALDH1A1MAPTHPGDHTTSMN1; SMN2 | |
| SCHEMBL287775 | 0.72 | GAA (0.36) | USP30ALDH1A1MAPTNPY5RHPGD | |
| SCHEMBL287259 | 0.71 | KMT2A (0.40) | ALDH1A1MAPTHPGDHTT | |
| SCHEMBL284518 | 0.70 | ALDH1A1 (0.34) | ALDH1A1MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL661997 | 0.67 | ALDH1A1 (0.49) | ALDH1A1NPY5RHTT | |
| SCHEMBL4160439 | 0.66 | TSHR (0.46) | ALDH1A1MAPTHPGDPBKSMN1; SMN2 | |
| SCHEMBL287097 | 0.64 | MMP1 (0.38) | ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427432-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2012-03-14 | — | — | EP | claimed |
| WO-2010128528-A2 | NOVEL HETEROCYCLIC COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-11 | — | — | WO | claimed |
| EP-2427432-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128528-A2 | NOVEL HETEROCYCLIC COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-11 | — | — | WO | disclosed |