Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287307 | 0.84 | ALDH1A1 (0.39) | HPGDRAB9ANPC1MEN1KMT2A | |
| SCHEMBL287408 | 0.79 | RAB9A (0.43) | HPGDRAB9ANPC1MEN1KMT2A | |
| SCHEMBL287518 | 0.77 | ALDH1A1 (0.35) | HPGDRAB9ANPC1L3MBTL1MEN1 | |
| SCHEMBL287825 | 0.75 | ALDH1A1 (0.34) | HPGDRAB9ANPC1MEN1KMT2A | |
| SCHEMBL287274 | 0.75 | ALDH1A1 (0.33) | HPGDRAB9ANPC1MEN1KMT2A | |
| SCHEMBL287419 | 0.73 | NPC1 (0.41) | RAB9ANPC1L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL286788 | 0.72 | MAPT (0.35) | HPGDRAB9ANPC1MEN1KMT2A | |
| SCHEMBL287139 | 0.71 | ALDH1A1 (0.38) | HPGDRAB9ANPC1L3MBTL1MEN1 | |
| SCHEMBL288004 | 0.70 | ALDH1A1 (0.48) | HPGDRAB9ANPC1L3MBTL1MEN1 | |
| SCHEMBL287813 | 0.69 | ALDH1A1 (0.45) | HPGDRAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427432-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128528-A2 | NOVEL HETEROCYCLIC COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-11 | — | — | WO | disclosed |