SCHEMBL28686258

SCHEMBL28686258

CCCCCCCCCCC(CCCCCCCC)Cc1c(C(N)=O)cc(C(N)=O)cc1C(N)=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
MAPK1 P28482 2/20 0.40
APAF1 O14727 1/20 0.40
RGS12 O14924 1/20 0.40
HSP90AA1 P07900 1/20 0.40
PRSS1 P07477 1/20 0.39
PRSS2 P07478 1/20 0.39
PRSS3 P35030 1/20 0.39
MAPT P10636 3/20 0.38
LMNA P02545 2/20 0.38
NR1I2 O75469 1/20 0.38
CHRM2 P08172 1/20 0.38
CYP3A4 P08684 1/20 0.38
ADRA2A P08913 1/20 0.38
OPRK1 P41145 1/20 0.38
HTR2B P41595 1/20 0.38
SLC6A3 Q01959 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
ALDH1A1 P00352 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22442276 0.88 TSHR (0.45) MEN1KMT2AMAPK1APAF1RGS12
SCHEMBL6536717 0.80 MEN1 (0.45) MEN1KMT2AMAPK1APAF1RGS12
SCHEMBL22342117 0.78 LMNA (0.44) MAPTLMNAGPR84FFAR1LCK
Formamide SCHEMBL22658137 0.77 PRSS1 (0.33) MEN1KMT2APRSS1PRSS2PRSS3
SCHEMBL16670906 0.76 MEN1 (0.40) MEN1KMT2AMAPK1APAF1RGS12
SCHEMBL27994814 0.74 PRSS1 (0.40) MEN1KMT2AMAPK1APAF1RGS12
SCHEMBL27681648 0.73 CYP3A4 (0.51) MEN1KMT2AMAPK1PRSS1PRSS2
SCHEMBL28678902 0.72 THRA (0.41) MEN1KMT2AMAPK1APAF1RGS12
SCHEMBL29253726 0.72 HDAC1 (0.41) MEN1KMT2AMAPK1APAF1RGS12
SCHEMBL29190820 0.72 HDAC1 (0.41) MEN1KMT2AMAPK1APAF1RGS12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114096602-B Composition and method for preparing sheets, films, fibers and shaped parts 洛桑联邦理工学院 (EPFL) 2024-02-13 CN disclosed
CN-114096602-A Compositions and methods for making sheets, films, fibers, and shaped parts 洛桑联邦理工学院 (EPFL) 2022-02-25 CN disclosed