SCHEMBL28679019

SCHEMBL28679019

Cc1c(F)cccc1C(C)(C)C#N

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
ACHE P22303 1/20 0.32
AR P10275 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
HSD11B1 P28845 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1626692 0.82 L3MBTL1 (0.38) L3MBTL1HSD11B1CA2
SCHEMBL780814 0.82 ACHE (0.36) L3MBTL1ACHEAR
SCHEMBL30966621 0.82 ACHE (0.36) L3MBTL1ACHEAR
SCHEMBL3866351 0.79 CA2 (0.34) L3MBTL1GABRA1GABRB2CA2
SCHEMBL7767484 0.79 L3MBTL1 (0.33) L3MBTL1
SCHEMBL8254661 0.77 CA2 (0.46) CHRM3ACHEGABRA1GABRB2HSD11B1
SCHEMBL16897504 0.77 ALDH1A1 (0.32) GABRA1GABRB2CA2
SCHEMBL20847883 0.77 ALDH1A1 (0.41) ARGABRA1GABRB2
SCHEMBL3932182 0.77 KIF11 (0.39) L3MBTL1ACHEARGABRA1GABRB2
SCHEMBL3535813 0.77 AR (0.40) L3MBTL1AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-215464371-U Reaction kettle for producing m-fluoro trimethyl benzyl cyanide 酒泉亚佳化学有限公司 2022-01-11 CN disclosed