Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 1.00 |
| ▸ | TOP1 | P11387 | 4/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.59 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.57 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | DHFR | P00374 | 1/20 | 0.54 |
| ▸ | MPO | P05164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28670758 | 0.91 | PTGS2 (0.83) | PTGS2TOP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL28930326 | 0.85 | TOP1 (0.78) | PTGS2TOP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL24172126 | 0.82 | PTGS2 (0.70) | PTGS2TOP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL28689408 | 0.81 | PTGS2 (0.68) | PTGS2TOP1KMT2AMEN1MT-CO2 | |
| SCHEMBL28661448 | 0.78 | TOP1 (1.00) | PTGS2TOP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL28670768 | 0.78 | PTGS2 (0.64) | PTGS2TOP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL28665402 | 0.77 | RXFP1 (0.80) | PTGS2TOP1NR1H4RXFP1 | |
| SCHEMBL9733796 | 0.77 | PTGS2 (0.66) | PTGS2TOP1KMT2AMEN1MT-CO2 | |
| SCHEMBL12189396 | 0.77 | KMT2A (0.69) | PTGS2TOP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL17079628 | 0.76 | MEN1 (0.71) | PTGS2TOP1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113651768-A | N-aryl anthranilamide compound and preparation and application thereof | 南华大学 | 2021-11-16 | — | — | CN | disclosed |