Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.83 |
| ▸ | TOP1 | P11387 | 5/20 | 0.83 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.53 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.50 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | DHFR | P00374 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28679794 | 0.91 | PTGS2 (1.00) | PTGS2TOP1RXFP1KDM4EMT-CO2 | |
| SCHEMBL28930326 | 0.82 | TOP1 (0.78) | PTGS2TOP1KDM4EMT-CO2KMT2A | |
| SCHEMBL24172126 | 0.78 | PTGS2 (0.70) | PTGS2TOP1RXFP1MT-CO2KMT2A | |
| SCHEMBL28689408 | 0.78 | PTGS2 (0.68) | PTGS2TOP1MT-CO2KMT2AMEN1 | |
| SCHEMBL12181724 | 0.77 | ALDH1A1 (0.65) | PTGS2KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL28661448 | 0.75 | TOP1 (1.00) | PTGS2TOP1MT-CO2KMT2AMEN1 | |
| SCHEMBL28670768 | 0.75 | PTGS2 (0.64) | PTGS2TOP1KDM4EMT-CO2KMT2A | |
| SCHEMBL9736935 | 0.74 | PTGS2 (0.71) | PTGS2TOP1RXFP1KDM4EMT-CO2 | |
| SCHEMBL24670251 | 0.74 | POLB (0.56) | RXFP1KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL9733796 | 0.73 | PTGS2 (0.66) | PTGS2TOP1RXFP1KDM4EMT-CO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113651768-A | N-aryl anthranilamide compound and preparation and application thereof | 南华大学 | 2021-11-16 | — | — | CN | disclosed |