Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 5/20 | 0.78 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.78 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.78 |
| ▸ | NPC1 | O15118 | 3/20 | 0.69 |
| ▸ | RAB9A | P51151 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.57 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.57 |
| ▸ | DHFR | P00374 | 1/20 | 0.57 |
| ▸ | MPO | P05164 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28661454 | 0.88 | MT-CO2 (1.00) | TOP1PTGS2MT-CO2NPC1RAB9A | |
| SCHEMBL24172126 | 0.87 | PTGS2 (0.70) | TOP1PTGS2MT-CO2NPC1RAB9A | |
| SCHEMBL28689408 | 0.86 | PTGS2 (0.68) | TOP1PTGS2MT-CO2NPC1RAB9A | |
| SCHEMBL28679794 | 0.85 | PTGS2 (1.00) | TOP1PTGS2MT-CO2NPC1RAB9A | |
| SCHEMBL28676345 | 0.83 | MEN1 (0.72) | TOP1PTGS2MT-CO2NPC1RAB9A | |
| SCHEMBL28670768 | 0.82 | PTGS2 (0.64) | TOP1PTGS2MT-CO2NPC1RAB9A | |
| SCHEMBL10062017 | 0.82 | NPC1 (1.00) | NPC1RAB9ALMNAALDH1A1HPGD | |
| SCHEMBL28670758 | 0.82 | PTGS2 (0.83) | TOP1PTGS2MT-CO2LMNAALDH1A1 | |
| SCHEMBL22819981 | 0.80 | NPC1 (0.69) | TOP1PTGS2MT-CO2NPC1RAB9A | |
| SCHEMBL9968725 | 0.80 | NPC1 (0.68) | TOP1PTGS2MT-CO2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113651768-A | N-aryl anthranilamide compound and preparation and application thereof | 南华大学 | 2021-11-16 | — | — | CN | disclosed |