Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.68 |
| ▸ | TOP1 | P11387 | 3/20 | 0.68 |
| ▸ | MT-CO2 | P00403 | 9/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.61 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.61 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
| ▸ | DHFR | P00374 | 1/20 | 0.61 |
| ▸ | MPO | P05164 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.61 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.61 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24172126 | 0.90 | PTGS2 (0.70) | PTGS2TOP1MT-CO2LMNAMEN1 | |
| SCHEMBL28687925 | 0.87 | MT-CO2 (0.76) | PTGS2TOP1MT-CO2LMNAMEN1 | |
| SCHEMBL28670768 | 0.86 | PTGS2 (0.64) | PTGS2TOP1MT-CO2LMNAMEN1 | |
| SCHEMBL28930326 | 0.86 | TOP1 (0.78) | PTGS2TOP1MT-CO2LMNAMEN1 | |
| SCHEMBL28679794 | 0.81 | PTGS2 (1.00) | PTGS2TOP1MT-CO2LMNAMEN1 | |
| SCHEMBL11781486 | 0.81 | HPGD (0.77) | LMNAMEN1KMT2ATDP1NPC1 | |
| SCHEMBL3237318 | 0.80 | MEN1 (0.75) | MT-CO2LMNAMEN1KMT2ANPC1 | |
| SCHEMBL9736935 | 0.80 | PTGS2 (0.71) | PTGS2TOP1MT-CO2LMNAMEN1 | |
| SCHEMBL7925344 | 0.79 | PTGS2 (0.76) | PTGS2TOP1MT-CO2LMNAMEN1 | |
| SCHEMBL9262003 | 0.79 | PTGS2 (0.69) | PTGS2TOP1MT-CO2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113651768-A | N-aryl anthranilamide compound and preparation and application thereof | 南华大学 | 2021-11-16 | — | — | CN | disclosed |