Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | LDHB | P07195 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28684424 | 0.86 | RAB9A (0.42) | ALDH1A1KDM4ELMNAHSD17B10RAB9A | |
| SCHEMBL28696581 | 0.81 | IDO1 (0.37) | ALDH1A1KDM4EHSD17B10NOTUMBAZ2B | |
| SCHEMBL3554094 | 0.81 | KMT2A (0.42) | KDM4ERAB9ANPC1S1PR4S1PR1 | |
| SCHEMBL28693273 | 0.79 | MTNR1A (0.49) | ALDH1A1KDM4ELMNAHSD17B10RAB9A | |
| SCHEMBL28706030 | 0.78 | BRD4 (0.45) | KDM4ELDHACREBBPMAPTHTT | |
| SCHEMBL1333179 | 0.77 | HTT (0.54) | ALDH1A1KDM4EHSD17B10RAB9ANPC1 | |
| SCHEMBL3567471 | 0.71 | ALDH1A1 (0.41) | ALDH1A1KDM4EHSD17B10RAB9ANPC1 | |
| SCHEMBL2475378 | 0.71 | NOTUM (0.45) | KDM4ERAB9ANPC1S1PR4S1PR1 | |
| SCHEMBL1271943 | 0.71 | PDGFRA (0.41) | LMNANOTUMBAZ2BCREBBPMAPT | |
| SCHEMBL6378148 | 0.71 | NOTUM (0.38) | ALDH1A1KDM4EHSD17B10RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057625-B | C2-acyloxy-3-indolinone derivative and preparation method and application thereof | 五邑大学 | 2023-11-24 | — | — | CN | disclosed |
| CN-114057625-A | C2-acyloxy-3-indolinone derivative and preparation method and application thereof | 五邑大学 | 2022-02-18 | — | — | CN | disclosed |