SCHEMBL28686231

SCHEMBL28686231

NC(Cc1c[nH]c(=O)[nH]c1=O)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.51
KMT2A Q03164 4/20 0.51
BLM P54132 4/20 0.51
KDM4E B2RXH2 3/20 0.51
LMNA P02545 3/20 0.51
PMP22 Q01453 3/20 0.51
TSHR P16473 3/20 0.51
MEN1 O00255 3/20 0.51
HIF1A Q16665 2/20 0.51
MPO P05164 1/20 0.51
ALDH1A1 P00352 3/20 0.48
CYP3A4 P08684 3/20 0.48
ALOX15 P16050 2/20 0.48
NFKB1 P19838 2/20 0.48
NPSR1 Q6W5P4 2/20 0.48
HSD17B10 Q99714 2/20 0.48
HTR1A P08908 1/20 0.48
ADORA3 P0DMS8 1/20 0.48
HTR2A P28223 1/20 0.48
HTR2C P28335 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30216007 0.84 GRIK1 (0.47) MAPTKMT2ABLMKDM4ELMNA
SCHEMBL27788682 0.84 KMT2A (0.49) MAPTKMT2ABLMKDM4ELMNA
SCHEMBL1062156 0.81 SMN1; SMN2 (0.50) LMNA
SCHEMBL26659419 0.79 SLC7A5 (0.51) MAPTKMT2ABLMKDM4ELMNA
SCHEMBL19307807 0.78 GAA (0.38)
SCHEMBL153254 0.77 ADRB1 (0.45) HTR1AHTR2AHTR2CSLC6A4HTR7
Dl-Phenylalanine SCHEMBL28370332 0.74 SLC7A5 (0.58) MAPTKMT2ABLMKDM4ELMNA
SCHEMBL1227718 0.73 GAA (0.47) MAPTLMNAPMP22TSHRALDH1A1
SCHEMBL7133034 0.73 ATAD2 (0.47)
Hydrogen Sulfide SCHEMBL30313488 0.72 GAA (0.45) MAPTLMNAPMP22TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220232831-A1 NOVEL NON-CODING HETEROCYCLIC AMINO ACIDS (NCHAA) AND THEIR USE AS HERBICIDES FORTEPHEST LTD. (IL) 2022-07-28 US claimed
EP-3983382-A1 NOVEL NON-CODING HETEROCYCLIC AMINO ACIDS (NCHAA) AND THEIR USE AS HERBICIDES Fortephest Ltd. (IL) 2022-04-20 EP claimed
CN-113939499-A Novel non-coding heterocyclic amino acids (NCHAA) and their use as herbicides 福提费斯特有限公司 2022-01-14 CN claimed
US-20220232831-A1 NOVEL NON-CODING HETEROCYCLIC AMINO ACIDS (NCHAA) AND THEIR USE AS HERBICIDES FORTEPHEST LTD. (IL) 2022-07-28 US disclosed
EP-3983382-A1 NOVEL NON-CODING HETEROCYCLIC AMINO ACIDS (NCHAA) AND THEIR USE AS HERBICIDES Fortephest Ltd. (IL) 2022-04-20 EP disclosed
CN-113939499-A Novel non-coding heterocyclic amino acids (NCHAA) and their use as herbicides 福提费斯特有限公司 2022-01-14 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220232831-A1 NOVEL NON-CODING HETEROCYCLIC AMINO ACIDS (NCHAA) AND THEIR USE AS HERBICIDES SLC43A1, NPPA, NAAA MAPT 3214/4885KMT2A 67/4885BLM 4627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.