O-Xylene

O-Xylene

SCHEMBL28686404

C[Si](C)(C)Oc1ccc(Br)cc1.Cc1ccccc1C

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.41
TSHR P16473 3/20 0.41
NPC1 O15118 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
ACHE P22303 1/20 0.40
ALDH1A1 P00352 6/20 0.38
MEN1 O00255 2/20 0.34
LMNA P02545 2/20 0.34
KMT2A Q03164 2/20 0.34
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
NR1H4 Q96RI1 1/20 0.34
MAPT P10636 3/20 0.33
MAPK1 P28482 3/20 0.33
TDP1 Q9NUW8 1/20 0.33
LDHA P00338 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3894497 0.87 CYP2A6 (0.42) RAB9ANPC1ALDH1A1MEN1LMNA
Toluene SCHEMBL28698834 0.86 ALDH1A1 (0.44) RAB9ATSHRNPC1SMN1; SMN2ACHE
SCHEMBL667750 0.85 CYP2A6 (0.40) RAB9ANPC1ALDH1A1MEN1LMNA
SCHEMBL10528634 0.81 MAPK1 (0.42) RAB9ANPC1SMN1; SMN2ALDH1A1MEN1
SCHEMBL4763549 0.75 CA1 (0.39) ACHEALDH1A1MEN1KMT2AMAPK1
SCHEMBL7688488 0.73 LMNA (0.65) RAB9AMEN1LMNAKMT2AMAOB
SCHEMBL7688132 0.73 MAPT (0.42) RAB9ANPC1MEN1LMNAKMT2A
SCHEMBL232678 0.73 CA4 (0.48) RAB9ATSHRNPC1MEN1LMNA
SCHEMBL8780512 0.72 CA4 (0.42) RAB9ATSHRNPC1SMN1; SMN2MEN1
SCHEMBL2016960 0.71 ACHE (0.50) RAB9ATSHRNPC1SMN1; SMN2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109912455-B Method for preparing 4-hydroxy-4' -cyanobiphenyl 宁夏中星显示材料有限公司 2022-03-01 CN disclosed