Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 5/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28825624 | 0.84 | GRIN2B (0.39) | GRIN2BGRIN1NFE2L2 | |
| SCHEMBL28825574 | 0.83 | GRIN1 (0.37) | GRIN2BGRIN1 | |
| SCHEMBL28825579 | 0.83 | NFE2L2 (0.46) | GRIN2BGRIN1NFE2L2 | |
| SCHEMBL28825697 | 0.81 | NFE2L2 (0.35) | GRIN2BGRIN1NFE2L2 | |
| SCHEMBL28696701 | 0.81 | ROCK2 (0.46) | GRIN2BGRIN1NFE2L2 | |
| SCHEMBL28825504 | 0.79 | ALOX5 (0.42) | GRIN2BGRIN1NFE2L2 | |
| SCHEMBL28825646 | 0.79 | GRIN2B (0.41) | GRIN2BGRIN1 | |
| SCHEMBL28825631 | 0.76 | ALDH1A1 (0.39) | GRIN2BGRIN1NFE2L2 | |
| SCHEMBL28825608 | 0.74 | GRIN2B (0.40) | GRIN2BGRIN1 | |
| SCHEMBL28949570 | 0.73 | HCAR2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114008052-A | Substituted pyrazolo-pyrazines and their use as GluN2B receptor modulators | 詹森药业有限公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-114007610-A | Substituted heteroaromatic pyrazolopyridines and their use as modulators of the GLUN2B receptor | 詹森药业有限公司 | 2022-02-01 | — | — | CN | disclosed |