Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PRCP | P42785 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP3 | P08254 | 2/20 | 0.36 |
| ▸ | MMP7 | P09237 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2866759 | 0.90 | ALDH1A1 (0.39) | ALDH1A1MAPTKDM4EPRCPKMT2A | |
| SCHEMBL17675682 | 0.86 | AAK1 (0.44) | MAPTKDM4EAAK1NPSR1TDP1 | |
| Hydrochloric Acid SCHEMBL17416399 | 0.79 | KMT2A (0.33) | ALDH1A1MAPTKDM4EPRCPKMT2A | |
| SCHEMBL2869957 | 0.73 | AADAT (0.35) | SMN1; SMN2 | |
| SCHEMBL2872640 | 0.72 | MMP1 (0.36) | AAK1MMP1MMP3MMP7 | |
| SCHEMBL2873832 | 0.72 | SCN10A (0.40) | KDM4EPRCPAAK1TAAR1LMNA | |
| SCHEMBL15158071 | 0.69 | PRCP (0.48) | ALDH1A1MAPTKDM4EPRCPKMT2A | |
| SCHEMBL4240617 | 0.67 | KMT2A (0.49) | MAPTKDM4EKMT2ASMN1; SMN2GAA | |
| SCHEMBL17493898 | 0.66 | AAK1 (0.59) | ALDH1A1KMT2AAAK1MMP1MMP3 | |
| SCHEMBL16720727 | 0.65 | MAPT (0.81) | ALDH1A1MAPTKDM4EKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010103306-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS ANTIVARAL AGENTS | ASTRAZENECA UK LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |