Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2E1 | Q9Y466 | 2/20 | 0.51 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.47 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | POLQ | O75417 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28697076 | 0.84 | ELOVL1 (0.52) | KCNJ5KCNJ3ANO1MEN1KMT2A | |
| SCHEMBL28700602 | 0.82 | NLRP3 (0.53) | NR2E1KCNJ5KCNJ3SIGMAR1MEN1 | |
| SCHEMBL28708127 | 0.82 | CA12 (0.53) | KCNJ5KCNJ3ANO1SIGMAR1MEN1 | |
| SCHEMBL28684562 | 0.82 | KCNJ5 (0.56) | NR2E1KCNJ5KCNJ3P2RX4 | |
| SCHEMBL28690666 | 0.82 | TDP1 (0.52) | ANO1MEN1MAPTKMT2ACYP1A2 | |
| SCHEMBL28706294 | 0.80 | KMT2A (0.58) | MEN1MAPTKMT2A | |
| SCHEMBL28706314 | 0.80 | KCNK3 (0.53) | MEN1KMT2AGAA | |
| SCHEMBL28933287 | 0.80 | MEN1 (0.68) | NR2E1SIGMAR1MEN1MAPTKMT2A | |
| SCHEMBL29389113 | 0.80 | MEN1 (0.68) | NR2E1SIGMAR1MEN1MAPTKMT2A | |
| SCHEMBL28704823 | 0.79 | MEN1 (0.57) | MEN1MAPTKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057630-B | Pirfenidone derivative and synthetic method and application thereof | 郑州大学 | 2023-06-02 | — | — | CN | claimed |
| CN-114057630-A | Pirfenidone derivative and synthetic method and application thereof | 郑州大学 | 2022-02-18 | — | — | CN | claimed |
| CN-114057630-B | Pirfenidone derivative and synthetic method and application thereof | 郑州大学 | 2023-06-02 | — | — | CN | disclosed |
| CN-114057630-A | Pirfenidone derivative and synthetic method and application thereof | 郑州大学 | 2022-02-18 | — | — | CN | disclosed |