Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.52 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28700650 | 0.89 | KMT2A (0.53) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL28697076 | 0.83 | ELOVL1 (0.52) | KMT2AMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL28684562 | 0.83 | KCNJ5 (0.56) | KDM4EALDH1A1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL28690666 | 0.83 | TDP1 (0.52) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL28708127 | 0.83 | CA12 (0.53) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL28704823 | 0.80 | MEN1 (0.57) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL28690641 | 0.80 | NR2E1 (0.51) | KMT2AMEN1MAPT | |
| SCHEMBL10079871 | 0.79 | ALDH1A1 (0.72) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL28684550 | 0.77 | MEN1 (0.61) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL1947868 | 0.76 | ALDH1A1 (0.68) | KMT2AMEN1KDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057630-B | Pirfenidone derivative and synthetic method and application thereof | 郑州大学 | 2023-06-02 | — | — | CN | claimed |
| CN-114057630-A | Pirfenidone derivative and synthetic method and application thereof | 郑州大学 | 2022-02-18 | — | — | CN | claimed |
| CN-114057630-B | Pirfenidone derivative and synthetic method and application thereof | 郑州大学 | 2023-06-02 | — | — | CN | disclosed |
| CN-114057630-A | Pirfenidone derivative and synthetic method and application thereof | 郑州大学 | 2022-02-18 | — | — | CN | disclosed |