Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8182070 | 0.95 | TSHR (0.41) | TSHRSMN1; SMN2CA2MAPK1ALDH1A1 | |
| SCHEMBL7923350 | 0.93 | LMNA (0.39) | TSHRSMN1; SMN2FDPSCA1EP300 | |
| SCHEMBL7923353 | 0.93 | LMNA (0.39) | TSHRSMN1; SMN2FDPSCA1EP300 | |
| SCHEMBL8902150 | 0.91 | TSHR (0.52) | TSHRSMN1; SMN2CA2MAPK1ALDH1A1 | |
| SCHEMBL20143287 | 0.91 | LMNA (0.43) | TSHRSMN1; SMN2DNM1FDPSEP300 | |
| SCHEMBL20143282 | 0.91 | LMNA (0.43) | TSHRSMN1; SMN2DNM1FDPSEP300 | |
| SCHEMBL8902146 | 0.91 | TSHR (0.52) | TSHRSMN1; SMN2CA2MAPK1ALDH1A1 | |
| SCHEMBL28181292 | 0.89 | TSHR (0.50) | TSHRSMN1; SMN2CA2MAPK1ALDH1A1 | |
| SCHEMBL27743293 | 0.88 | TSHR (0.36) | TSHRSMN1; SMN2CA2MAPK1 | |
| SCHEMBL8601150 | 0.84 | TSHR (0.45) | TSHRSMN1; SMN2CA2MAPK1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113891882-A | Method for producing dihydroisoxazole | 组合化学工业株式会社 | 2022-01-04 | — | — | CN | disclosed |