SCHEMBL8902146

SCHEMBL8902146

CCCCC(/C=N/O)CC

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
CA2 P00918 7/20 0.40
MAPK1 P28482 1/20 0.40
ALDH1A1 P00352 3/20 0.38
CA1 P00915 4/20 0.34
TDP1 Q9NUW8 1/20 0.33
CYP3A4 P08684 1/20 0.32
FDPS P14324 1/20 0.32
DNM1 Q05193 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8902150 1.00 TSHR (0.52) TSHRSMN1; SMN2CA2MAPK1ALDH1A1
SCHEMBL28181292 0.98 TSHR (0.50) TSHRSMN1; SMN2CA2MAPK1ALDH1A1
SCHEMBL8601150 0.93 TSHR (0.45) TSHRSMN1; SMN2CA2MAPK1CA1
SCHEMBL28690695 0.91 TSHR (0.44) TSHRSMN1; SMN2CA2MAPK1ALDH1A1
SCHEMBL8182070 0.86 TSHR (0.41) TSHRSMN1; SMN2CA2MAPK1ALDH1A1
SCHEMBL28279869 0.86
SCHEMBL8600053 0.86
SCHEMBL7923353 0.84 LMNA (0.39) TSHRSMN1; SMN2CA1FDPS
SCHEMBL7923350 0.84 LMNA (0.39) TSHRSMN1; SMN2CA1FDPS
SCHEMBL6503063 0.83 FAAH (0.41) TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0557274-B1 RECOVERY OF PALLADIUM HENKEL CORP (US) 1994-09-14 EP claimed
EP-0557274-A1 RECOVERY OF PALLADIUM. HENKEL CORP (US) 1993-09-01 EP claimed
WO-1992008813-A1 RECOVERY OF PALLADIUM HENKEL CORPORATION (US) 1992-05-29 WO claimed
US-4528167-A Selective solvent extraction using organophosphorus and carboxylic acids and a non-chelating aldehyde oxime COUNCIL FOR MINERAL TECHNOLOGY (ZA) 1985-07-09 US claimed
JP-61238927-A None JP disclosed
US-5654458-A PALLADIUM CHLORIDE COMPLEX WITH ETHER OXIME HENKEL CORPORATION (US) 1997-08-05 US disclosed
EP-0557274-B1 RECOVERY OF PALLADIUM HENKEL CORP (US) 1994-09-14 EP disclosed
EP-0557274-A1 RECOVERY OF PALLADIUM. HENKEL CORP (US) 1993-09-01 EP disclosed
WO-1992008813-A1 RECOVERY OF PALLADIUM HENKEL CORPORATION (US) 1992-05-29 WO disclosed
US-4865824-A Process for recovering gallium from basic aqueous sodium aluminate solutions by means of liquid-liquid extraction HOECHST AKTIENGESELLSCHAFT (DE) 1989-09-12 US disclosed
JP-S61238927-A METHOD FOR RECOVERING PALLADIUM DAIHACHI KAGAKU KOGYOSHO:KK 1986-10-24 JP disclosed
US-4528167-A Selective solvent extraction using organophosphorus and carboxylic acids and a non-chelating aldehyde oxime COUNCIL FOR MINERAL TECHNOLOGY (ZA) 1985-07-09 US disclosed