SCHEMBL8601150

SCHEMBL8601150

CCCCCC(C=NO)CC

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
LMNA P02545 1/20 0.37
OPRM1 P35372 1/20 0.34
FDPS P14324 4/20 0.34
CA2 P00918 1/20 0.34
MAPK1 P28482 1/20 0.34
MAPT P10636 2/20 0.34
TRPA1 O75762 1/20 0.34
DDAH1 O94760 1/20 0.34
GAPDH P04406 1/20 0.34
GPR84 Q9NQS5 3/20 0.33
SPHK1 Q9NYA1 1/20 0.33
FFAR1 O14842 1/20 0.33
CA1 P00915 1/20 0.33
GRIK1 P39086 1/20 0.32
SLC1A2 P43004 1/20 0.32
SLC1A1 P43005 1/20 0.32
GRIK2 Q13002 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8902146 0.93 TSHR (0.52) TSHRSMN1; SMN2FDPSCA2MAPK1
SCHEMBL8902150 0.93 TSHR (0.52) TSHRSMN1; SMN2FDPSCA2MAPK1
SCHEMBL28181292 0.91 TSHR (0.50) TSHRSMN1; SMN2FDPSCA2MAPK1
SCHEMBL7923353 0.91 LMNA (0.39) TSHRSMN1; SMN2LMNAOPRM1FDPS
SCHEMBL7923350 0.91 LMNA (0.39) TSHRSMN1; SMN2LMNAOPRM1FDPS
SCHEMBL6503063 0.89 FAAH (0.41) LMNAMAPTFFAR1
SCHEMBL20143282 0.89 LMNA (0.43) TSHRSMN1; SMN2LMNAFDPSMAPT
SCHEMBL20143287 0.89 LMNA (0.43) TSHRSMN1; SMN2LMNAFDPSMAPT
SCHEMBL28690695 0.84 TSHR (0.44) TSHRSMN1; SMN2LMNAFDPSCA2
SCHEMBL8600053 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5412006-A Electrorheological cels and a method for the preparation thereof DOW CORNING CORPORATION (US) 1995-05-02 US claimed
EP-4499414-A1 FILM, FILM-COATED OBJECT AND METHOD FOR PRODUCING A FILM-COATED OBJECT LEONHARD KURZ Stiftung & Co. KG (DE) 2025-02-05 EP disclosed
EP-3668721-B1 METHOD FOR PRODUCING A FILM-COATED ARTICLE AND FILM-COATED ARTICLE LEONHARD KURZ STIFTUNG & CO KG (DE) 2024-05-29 EP disclosed
CN-116854681-A Hormone receptor modulators for the treatment of metabolic conditions and disorders 阿德利克斯股份有限公司 2023-10-10 CN disclosed
WO-2023186460-A1 FILM, FILM-COATED OBJECT AND METHOD FOR PRODUCING A FILM-COATED OBJECT LEONHARD KURZ STIFTUNG & CO. KG (DE) 2023-10-05 WO disclosed
CN-110177783-B Hormone receptor modulators for the treatment of metabolic conditions and disorders 阿德利克斯股份有限公司 2023-06-06 CN disclosed
CN-111278659-A Transfer foil, method for producing a foil-coated article, and foil-coated article 雷恩哈德库兹基金两合公司 2020-06-12 CN disclosed
EP-0672745-B1 Electrorheological gels and method for preparation DOW CORNING (US) 1998-02-25 EP disclosed
EP-0672745-A2 Electrorheological gels and method for preparation DOW CORNING CORPORATION (US) 1995-09-20 EP disclosed
US-5412006-A Electrorheological cels and a method for the preparation thereof DOW CORNING CORPORATION (US) 1995-05-02 US disclosed
EP-0326516-A2 Method of making patterns CIBA-GEIGY AG (CH) 1989-08-02 EP disclosed
US-4393238-A Method for the production of blocked isocyanates AKZO NV (NL) 1983-07-12 US disclosed
US-4215175-A Non-woven fibers coated with a polymer of ethylenically unsaturated blocked aromatic diisocyanates THE B. F. GOODRICH COMPANY (US) 1980-07-29 US disclosed
US-4191833-A BLOCKED WITH PYRAZOLE, ADDITION POLYMERS THE B.F. GOODRICH COMPANY (US) 1980-03-04 US disclosed
US-4191834-A BLOCKED WITH BENZIMIDAZOLE, ADDITION POLYMERS THE B.F. GOODRICH COMPANY (US) 1980-03-04 US disclosed
US-4190582-A Ethylenically unsaturated blocked aromatic diisocyanates THE B. F. GOODRICH COMPANY (US) 1980-02-26 US disclosed
US-4189601-A ADHESIVES, BINDERS FOR NONWOVEN FABRICS THE B. F. GOODRICH COMPANY (US) 1980-02-19 US disclosed
US-4113958-A POLYMERS USEFUL AS ADHESIVES AND BINDERS THE B. F. GOODRICH COMPANY (US) 1978-09-12 US disclosed
US-4101491-A USEFUL AS BINDERS FOR NONWOVEN FIBERS THE B. F. GOODRICH COMPANY (US) 1978-07-18 US disclosed
US-4008247-A POLYMER INTERMEDIATE THE B. F. GOODRICH COMPANY (US) 1977-02-15 US disclosed