Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28545542 | 0.81 | NPC1 (0.35) | NPC1RAB9AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL28542086 | 0.72 | NLRP3 (0.32) | — | |
| SCHEMBL24013809 | 0.71 | IDO1 (0.32) | FPR2PROKR1 | |
| SCHEMBL30365794 | 0.71 | IDO1 (0.32) | FPR2PROKR1 | |
| SCHEMBL28689825 | 0.70 | FAAH (0.33) | NPC1FAAHRAB9AMAPTSMN1; SMN2 | |
| SCHEMBL28550457 | 0.69 | NLRP3 (0.45) | — | |
| SCHEMBL28490230 | 0.69 | NPC1 (0.34) | NPC1FAAHRAB9AMAPTSMN1; SMN2 | |
| SCHEMBL28553925 | 0.68 | ALDH1A1 (0.32) | — | |
| SCHEMBL8086287 | 0.67 | PKM (0.34) | NPC1RAB9AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL28711180 | 0.67 | NPC1 (0.33) | NPC1RAB9AMAPTSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114127058-B | Heterocyclic compound, pharmaceutical composition and application thereof | 深圳国顺康医药科技有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-114127058-A | Heterocyclic compound, pharmaceutical composition and application thereof | 北京国鸿生物医药科技有限公司 | 2022-03-01 | — | — | CN | disclosed |