SCHEMBL4858558

SCHEMBL4858558

CC(C)(C)Oc1ccc(CC[Si](C)(C)Cl)cc1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 7/20 0.42
PPARG P37231 6/20 0.35
ALDH1A1 P00352 3/20 0.35
PPARD Q03181 3/20 0.35
FABP2 P12104 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ACACB O00763 1/20 0.34
KDM4E B2RXH2 2/20 0.33
PKM P14618 1/20 0.33
MAPT P10636 1/20 0.33
TAAR1 Q96RJ0 1/20 0.32
TBXAS1 P24557 2/20 0.32
TSHR P16473 1/20 0.31
CALM1 P0DP23 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10338732 0.89 PPARA (0.42) PPARAPPARGALDH1A1PPARDFABP2
SCHEMBL15945052 0.81 PPARA (0.41) PPARAPPARGALDH1A1PPARDFABP2
SCHEMBL3195033 0.80 LMNA (0.38) TAAR1
SCHEMBL16035907 0.79 PPARA (0.42) PPARAPPARDSMN1; SMN2KDM4ETAAR1
SCHEMBL7110250 0.78 TAAR1 (0.34) PPARASMN1; SMN2TAAR1CALM1
SCHEMBL6667517 0.77 PPARA (0.66) PPARAPPARGALDH1A1ACACBKDM4E
SCHEMBL3043486 0.76 PPARA (0.41) PPARAPPARGALDH1A1PPARDFABP2
SCHEMBL2869439 0.76 KCNH2 (0.46)
SCHEMBL91178 0.75 THRB (0.46) PPARAPPARGALDH1A1ACACBTAAR1
SCHEMBL14998990 0.75 PPARA (0.44) PPARAPPARGALDH1A1PPARDACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7439010-B2 Alkali-soluble siloxane polymer, positive type resist composition, resist pattern, process for forming the same, electronic device and process for manufacturing the same FUJITSU LIMITED (JP) 2008-10-21 US disclosed
US-20050221227-A1 Alkali-soluble siloxane polymer, positive type resist composition, resist pattern, process for forming the same, electronic device and process for manufacturing the same FUJITSU LIMITED (JP) 2005-10-06 US disclosed
US-6949324-B2 Alkali-soluble siloxane polymer, positive type resist composition, resist pattern, process for forming the same, electronic device and process for manufacturing the same FUJITSU LIMITED (JP) 2005-09-27 US disclosed
US-20030211407-A1 Alkali-soluble siloxane polymer, positive type resist composition, resist pattern, process for forming the same, electronic device and process for manufacturing the same FUJITSU LIMITED (JP) 2003-11-13 US disclosed
EP-1349007-A1 Photosensitive Paste SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-10-01 EP disclosed
US-4946921-A POLYSILICATE CONTAINING HYDROXYPHENYL GROUP TORAY SILICONE COMPANY LIMITED (JP) 1990-08-07 US disclosed
EP-0342648-A2 Alkali-soluble organopolysiloxane TORAY SILICONE COMPANY, LIMITED (JP) 1989-11-23 EP disclosed