SCHEMBL4848439

SCHEMBL4848439

C[Si](C)(Cl)CCc1ccc(CCl)cc1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.34
CA1 P00915 2/20 0.34
LMNA P02545 1/20 0.34
TAAR1 Q96RJ0 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3195033 0.91 LMNA (0.38) CA2LMNATAAR1
SCHEMBL4848522 0.86 CA2 (0.34) CA2CA1LMNATAAR1L3MBTL1
SCHEMBL11207785 0.85 THRA (0.35) LMNA
SCHEMBL6671164 0.82 TAAR1 (0.48) CA2LMNATAAR1L3MBTL1
SCHEMBL22825991 0.82 CA2 (0.34) CA2CA1LMNATAAR1L3MBTL1
SCHEMBL926567 0.81 CA2 (0.37) CA2CA1TAAR1L3MBTL1
SCHEMBL8850274 0.80 LMNA (0.33) LMNA
SCHEMBL11848944 0.80 CA1 (0.33) CA2CA1LMNA
SCHEMBL4850067 0.79 TSHR (0.38) TAAR1
SCHEMBL523595 0.79 TDP1 (0.48) LMNATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7463400-B1 Electrochromic display device FUJI XEROX CO., LTD. (JP) 2008-12-09 US disclosed
US-7053167-B2 Silsesquioxane derivative having functional group CHISSO CORPORATION (JP) 2006-05-30 US disclosed
US-20060089504-A1 Silsesquioxane derivative having functional group ITO KENYA 2006-04-27 US disclosed
EP-0969007-B1 Method of making an aromatic chlorosilane compound by a hydrosilation reaction DOW CORNING ASIA LTD (JP) 2004-09-22 EP disclosed
US-20040068074-A1 Production process for silsesquioxane derivative having functional group and silsesquioxane derivative JNC CORPORATION (JP) 2004-04-08 US disclosed
US-6284365-B1 FOR CONTROLLING PHYSICAL PROPERTIES OF SURFACE AND INTERFACE OF SOLID ARTICLE SUCH AS WETTABILITY, ADHESIVE PROPERTY, SURFACE ENERGY, DISPERSABILITY, CHEMICAL RESISTANCE FUJI XEROX CO., LTD. (JP) 2001-09-04 US disclosed
US-6054602-A Method of making an aromatic chlorosilane compound by a hydrosilation reaction DOW CORNING ASIA, LTD. (JP) 2000-04-25 US disclosed
EP-0969007-A2 Method of making an aromatic chlorosilane compound by a hydrosilation reaction Dow Corning Asia, Ltd. (JP) 2000-01-05 EP disclosed
US-5298532-A Vinyl-siloxane block polymer, release coating MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-03-29 US disclosed
US-5093385-A Block Polymerization MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-03-03 US disclosed
EP-0434335-A2 A method of accelerating photoiniferter polymerization, polymer produced thereby, and product produced therewith MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-06-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060089504-A1 Silsesquioxane derivative having functional group SFXN1, STS, SRM CA2 35/4885CA1 24/4885LMNA 2228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.