Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 4/20 | 0.41 |
| ▸ | HNF4A | P41235 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28706006 | 0.81 | LDHA (0.43) | PTPN1AKR1C2AKR1C3PTGDR2BACE1 | |
| SCHEMBL28615493 | 0.80 | PTPN1 (0.43) | PTPN1AKR1C2AKR1C1HNF4AAKR1C3 | |
| SCHEMBL29702020 | 0.75 | ALDH1A1 (0.43) | PTPN1AKR1C2AKR1C3PTGDR2FOLH1 | |
| SCHEMBL2174123 | 0.75 | HNF4A (0.58) | PTPN1AKR1C2AKR1C1HNF4AFOLH1 | |
| SCHEMBL2524408 | 0.75 | PTPN1 (0.46) | PTPN1AKR1C2AKR1C1HNF4AAKR1C3 | |
| SCHEMBL667582 | 0.72 | PTPN1 (0.59) | PTPN1AKR1C2AKR1C1HNF4AAKR1C3 | |
| SCHEMBL7772423 | 0.72 | PTPN1 (0.59) | PTPN1AKR1C2AKR1C1HNF4AAKR1C3 | |
| SCHEMBL27587157 | 0.72 | PTPN1 (0.44) | PTPN1AKR1C2AKR1C1HNF4AAKR1C3 | |
| SCHEMBL5934445 | 0.72 | HNF4A (0.54) | PTPN1AKR1C2AKR1C1HNF4AAKR1C3 | |
| SCHEMBL6655044 | 0.72 | TTR (0.41) | PTPN1HNF4AGFERFABP4RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113943287-A | Polycyclic aromatic compound and application thereof in electroluminescent device | 清华大学 | 2022-01-18 | — | — | CN | disclosed |