SCHEMBL29702020

SCHEMBL29702020

O=C(O)c1c(C(F)(F)F)ccc(-c2ccccc2)c1C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
LDHA P00338 1/20 0.40
FOLH1 Q04609 1/20 0.40
KMO O15229 2/20 0.39
FABP4 P15090 1/20 0.38
PLK1 P53350 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
AKR1C3 P42330 1/20 0.37
AKR1C2 P52895 1/20 0.37
FFAR4 Q5NUL3 1/20 0.37
PTPN1 P18031 1/20 0.37
ANO1 Q5XXA6 1/20 0.36
BACE1 P56817 1/20 0.36
CDC14B O60729 1/20 0.36
CDC14A Q9UNH5 1/20 0.36
DAO P14920 1/20 0.36
PTGDR2 Q9Y5Y4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28678120 0.87 CYP2C8 (0.49) FOLH1HDAC6AKR1C3AKR1C2ANO1
SCHEMBL28636307 0.86 ALDH1A1 (0.45) ALDH1A1HPGDLDHAFOLH1KMO
SCHEMBL4229287 0.85 AKR1C3 (0.55) FOLH1KMOHDAC6AKR1C3AKR1C2
SCHEMBL29188682 0.82 ALDH1A1 (0.42) ALDH1A1HPGDLDHAFOLH1KMO
SCHEMBL28706006 0.82 LDHA (0.43) ALDH1A1HPGDLDHAKMOFABP4
SCHEMBL16394743 0.82 ALDH1A1 (0.42) ALDH1A1HPGDKMOPLK1AKR1C3
SCHEMBL4858143 0.82 PTGDR2 (0.37) ALDH1A1HPGDLDHAFOLH1KMO
SCHEMBL4849605 0.80 DAO (0.44) ALDH1A1HPGDLDHAKMOPLK1
SCHEMBL344492 0.79 ALDH1A1 (0.49) ALDH1A1HPGDFOLH1KMOFABP4
SCHEMBL6677822 0.79 TAS2R14 (0.44) ALDH1A1HPGDFOLH1KMOPLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114621270-A Fused aromatic compound and application thereof in electroluminescent device 清华大学 2022-06-14 CN disclosed