Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28708992 | 0.89 | CHRNA7 (0.46) | DRD2SIGMAR1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL28701655 | 0.84 | SIRT6 (0.46) | ALDH1A1SMN1; SMN2KDM4EGAA | |
| SCHEMBL28689807 | 0.83 | AR (0.38) | SIGMAR1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL28685736 | 0.82 | IGF1R (0.38) | SIGMAR1ALDH1A1SMN1; SMN2KDM4EGAA | |
| SCHEMBL1459581 | 0.79 | AR (0.39) | SIGMAR1ALDH1A1SMN1; SMN2KDM4EGAA | |
| SCHEMBL28701674 | 0.78 | CTSS (0.34) | SIGMAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1899182 | 0.77 | PDK2 (0.39) | SIGMAR1ALDH1A1SMN1; SMN2KDM4EGAA | |
| SCHEMBL28685696 | 0.77 | MAPT (0.44) | ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL28691839 | 0.77 | DRD2 (0.62) | DRD2SIGMAR1DRD3 | |
| SCHEMBL27993852 | 0.75 | LMNA (0.42) | ALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114127065-A | Compounds for the treatment of neurodegenerative diseases and cancer | 鸿仪有限责任公司 | 2022-03-01 | — | — | CN | claimed |
| CN-114127065-A | Compounds for the treatment of neurodegenerative diseases and cancer | 鸿仪有限责任公司 | 2022-03-01 | — | — | CN | disclosed |