Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | RAD52 | P43351 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KHK | P50053 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28698178 | 0.89 | DRD2 (0.49) | GAASMN1; SMN2KDM4ESIGMAR1DRD3 | |
| SCHEMBL28689807 | 0.86 | AR (0.38) | SMN1; SMN2MAPTKDM4ESIGMAR1ALDH1A1 | |
| SCHEMBL28685736 | 0.85 | IGF1R (0.38) | GAASMN1; SMN2MAPTGFERKDM4E | |
| SCHEMBL28701655 | 0.83 | SIRT6 (0.46) | GAASMN1; SMN2MAPTGFERKDM4E | |
| SCHEMBL1459581 | 0.81 | AR (0.39) | GAASMN1; SMN2MAPTKDM4ESIGMAR1 | |
| SCHEMBL28701674 | 0.81 | CTSS (0.34) | SMN1; SMN2MAPTSIGMAR1ALDH1A1TSHR | |
| SCHEMBL1899182 | 0.80 | PDK2 (0.39) | GAASMN1; SMN2MAPTKDM4ESIGMAR1 | |
| SCHEMBL28685696 | 0.79 | MAPT (0.44) | SMN1; SMN2MAPTKDM4EKHKHRH3 | |
| SCHEMBL17728862 | 0.77 | GAA (0.56) | CHRNA7GAARAD52SMN1; SMN2MAPT | |
| SCHEMBL27993852 | 0.77 | LMNA (0.42) | SMN1; SMN2MAPTKDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114127065-A | Compounds for the treatment of neurodegenerative diseases and cancer | 鸿仪有限责任公司 | 2022-03-01 | — | — | CN | claimed |
| CN-114127065-A | Compounds for the treatment of neurodegenerative diseases and cancer | 鸿仪有限责任公司 | 2022-03-01 | — | — | CN | disclosed |