Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 3/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL746562 | 0.76 | NOTUM (0.44) | BRPF1CCNB2CDK1CCNB1GSK3B | |
| SCHEMBL256751 | 0.74 | KMT2A (0.46) | BRPF1CCNB2CDK1CCNB1GSK3B | |
| SCHEMBL15079238 | 0.73 | BRPF1 (0.38) | BRPF1CCNB2CDK1CCNB1GSK3B | |
| SCHEMBL26621513 | 0.73 | MEN1 (0.44) | BRPF1CCNB2CDK1CCNB1GSK3B | |
| SCHEMBL745354 | 0.73 | GSK3B (0.44) | BRPF1CCNB2CDK1CCNB1GSK3B | |
| SCHEMBL24080922 | 0.73 | BRPF1 (0.40) | BRPF1CCNB2CDK1CCNB1GSK3B | |
| SCHEMBL5441241 | 0.73 | BRPF1 (0.40) | BRPF1CCNB2CDK1CCNB1GSK3B | |
| SCHEMBL3484140 | 0.73 | DRD2 (0.40) | BRPF1CCNB2CDK1CCNB1GSK3B | |
| SCHEMBL18069197 | 0.71 | LMNA (0.45) | BRPF1CCNB2CDK1CCNB1GSK3B | |
| SCHEMBL13533089 | 0.70 | FAAH (0.42) | BRPF1CCNB2CDK1CCNB1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651208-B | N-aryl sulfonamide compound, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2022-01-04 | — | — | CN | disclosed |