SCHEMBL28700294

SCHEMBL28700294

O=C(Nc1cc[nH]n1)NS(=O)(=O)c1cc[nH]n1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NLRP3 Q96P20 2/20 0.34
GAA P10253 2/20 0.33
PKM P14618 1/20 0.33
CA12 O43570 4/20 0.32
CA1 P00915 4/20 0.32
CA2 P00918 4/20 0.32
CA9 Q16790 4/20 0.32
KMT2A Q03164 2/20 0.31
CA4 P22748 1/20 0.31
CA6 P23280 1/20 0.31
CA5A P35218 1/20 0.31
CA7 P43166 1/20 0.31
CA13 Q8N1Q1 1/20 0.31
CA14 Q9ULX7 1/20 0.31
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10614269 0.81 NLRP3 (0.41) LMNAKDM4EALDH1A1NLRP3GAA
SCHEMBL8553736 0.80 LMNA (0.60) LMNAKDM4EALDH1A1SMN1; SMN2NLRP3
SCHEMBL729334 0.77 MEN1 (0.39) KMT2AMEN1
SCHEMBL28335271 0.76
Potassium SCHEMBL29492940 0.74 NLRP3 (0.64) NLRP3
SCHEMBL3064600 0.70
SCHEMBL7808118 0.70
SCHEMBL20029229 0.69 ALDH1A1 (0.42) ALDH1A1GAAPKMKMT2AMEN1
SCHEMBL13038790 0.69 SMN1; SMN2 (0.59) ALDH1A1SMN1; SMN2KMT2AMEN1
SCHEMBL14559560 0.69 GAA (0.43) SMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110343102-B Substituted pyrazolyl pyrazole sulfonylurea compound or its salt as pesticide acceptable, composition and use thereof 海利尔药业集团股份有限公司 2022-02-18 CN claimed
CN-110343102-B Substituted pyrazolyl pyrazole sulfonylurea compound or its salt as pesticide acceptable, composition and use thereof 海利尔药业集团股份有限公司 2022-02-18 CN disclosed