SCHEMBL729334

SCHEMBL729334

NC(=O)NS(=O)(=O)c1cc[nH]n1

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
MMP2 P08253 1/20 0.35
MMP14 P50281 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28026585 0.77 MEN1 (0.31) MEN1KMT2A
SCHEMBL29067528 0.77 ALDH1A1 (0.34) MEN1KMT2A
SCHEMBL28700294 0.77 LMNA (0.36) MEN1KMT2A
SCHEMBL28026580 0.76 MEN1 (0.30) MEN1KMT2A
Ammonia Solution, Strong SCHEMBL28026105 0.76 MEN1 (0.30) MEN1KMT2A
SCHEMBL7808118 0.74
SCHEMBL10614269 0.73 NLRP3 (0.41) MEN1KMT2A
Water SCHEMBL8940230 0.73
SCHEMBL19115314 0.73 LMNA (0.40)
SCHEMBL9602866 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 286 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7557067-B2 Pyrazole sulfonylurea compound and herbicide NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-07-07 US claimed
US-20080064600-A1 Pyrazole Sulfonylurea Compound and Herbicide NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2008-03-13 US claimed
EP-1748047-A1 PYRAZOLE SULFONYLUREA COMPOUND AND HERBICIDE Nissan Chemical Industries, Ltd. (JP) 2007-01-31 EP claimed
EP-1008297-B1 Mixtures of herbicides and antidotes BAYER CROPSCIENCE GMBH (DE) 2003-03-19 EP claimed
EP-0492367-B1 Mixtures of herbicides and antidotes AVENTIS CROPSCIENCE GMBH (DE) 2000-09-27 EP claimed
US-5698539-A PLANT SAFENING AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1997-12-16 US claimed
US-5488027-A Herbicide-safener combinations containing sulfonylurea or imidazolinone herbicides HOECHST AKTIENGESELLSCHAFT (DE) 1996-01-30 US claimed
JP-61218503-A None JP disclosed
JP-63048204-A None JP disclosed
JP-6192017-A None JP disclosed
JP-61233604-A None JP disclosed
JP-61191602-A None JP disclosed
JP-63295503-A None JP disclosed
JP-H00640824-A 0001-01-01 JP disclosed
JP-S06348204-A 0001-01-01 JP disclosed
JP-S0648907-A 0001-01-01 JP disclosed
JP-S0645504-A 0001-01-01 JP disclosed
JP-S06248604-A 0001-01-01 JP disclosed
JP-S0648910-A 0001-01-01 JP disclosed
JP-S06118703-A 0001-01-01 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080064600-A1 Pyrazole Sulfonylurea Compound and Herbicide GLP1R, MSRB3, PDXK MEN1 609/4885KMT2A 1139/4885MMP2 3312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.