Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 2/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 2/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28707120 | 0.83 | HSPA5 (0.55) | HSPA5BACE1CYP1A2KEAP1ALOX5 | |
| SCHEMBL50409 | 0.81 | BACE1 (0.62) | HSPA5BACE1CYP1A2ALOX5GABRA1 | |
| SCHEMBL8370360 | 0.77 | HSD17B1 (0.64) | BACE1CYP1A2GABRA1GABRB2MEN1 | |
| SCHEMBL2577181 | 0.76 | KEAP1 (0.70) | HSPA5MPOKEAP1ALOX5MEN1 | |
| SCHEMBL1616373 | 0.75 | HIF1A (0.54) | HSPA5MEN1KMT2AUSP2LMNA | |
| SCHEMBL49745 | 0.74 | HSPA5 (1.00) | HSPA5MPOKEAP1LMNAMAPT | |
| SCHEMBL29357407 | 0.74 | HSPA5 (1.00) | HSPA5MPOKEAP1LMNAMAPT | |
| SCHEMBL5208612 | 0.74 | ALOX5 (0.57) | BACE1CYP1A2ALOX5GABRA1GABRB2 | |
| SCHEMBL51661 | 0.74 | ALOX5 (0.61) | HSPA5BACE1CYP1A2ALOX5MEN1 | |
| SCHEMBL29738649 | 0.73 | MEN1 (0.62) | BACE1CYP1A2KEAP1ALOX5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110431177-B | Curable composition, in particular as primer for the adhesion of crystalline rubbers to substrates | 汉高股份有限及两合公司 | 2022-03-01 | — | — | CN | disclosed |