Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8621288 | 0.83 | ALDH1A1 (0.44) | LMNAMAPK1CYP2D6SRCMME | |
| SCHEMBL29001941 | 0.83 | ALDH1A1 (0.44) | LMNAMAPK1CYP2D6SRCMME | |
| SCHEMBL8621292 | 0.83 | ALDH1A1 (0.44) | LMNAMAPK1CYP2D6SRCMME | |
| SCHEMBL19418994 | 0.81 | NAALAD2 (0.57) | LMNAMAPK1NAALAD2 | |
| SCHEMBL8230711 | 0.80 | MME (0.41) | LMNAMAPK1CYP2D6SRCMME | |
| SCHEMBL3679033 | 0.80 | PTPN9 (0.41) | LMNAMMETGFBR1 | |
| SCHEMBL594168 | 0.75 | GSR (0.44) | CYP2D6SRCMMENAALAD2 | |
| SCHEMBL31480057 | 0.75 | KDM4E (0.48) | LMNAMAPK1CYP2D6CES2CES1 | |
| SCHEMBL8575470 | 0.72 | TGFBR1 (0.58) | MMETGFBR1NAALAD2 | |
| SCHEMBL7222907 | 0.71 | MME (0.68) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110548150-B | Application of compound pharmaceutical composition in preparation of medicine for treating acute kidney injury | 中国药科大学 | 2022-03-08 | — | — | CN | disclosed |
| CN-110548150-A | Application of compound pharmaceutical composition in preparation of medicine for treating acute kidney injury | UNIV CHINA PHARMA | 2019-12-10 | — | — | CN | disclosed |