Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGAM1 | P18669 | 5/20 | 0.68 |
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | MAOA | P21397 | 4/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | DAPK1 | P53355 | 3/20 | 0.62 |
| ▸ | BCL2 | P10415 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.62 |
| ▸ | RECQL | P46063 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.62 |
| ▸ | APEX1 | P27695 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27939359 | 0.98 | PGAM1 (0.66) | PGAM1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6905576 | 0.91 | PGAM1 (0.53) | PGAM1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6901828 | 0.89 | PGAM1 (0.51) | PGAM1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL16950304 | 0.87 | PGAM1 (0.50) | PGAM1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL17038036 | 0.86 | MAOA (0.63) | PGAM1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL17038035 | 0.85 | MAOA (0.65) | PGAM1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL159669 | 0.84 | PGAM1 (0.56) | PGAM1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL29643579 | 0.84 | PGAM1 (0.56) | PGAM1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL17494572 | 0.83 | PGAM1 (0.52) | PGAM1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5246506 | 0.82 | PGAM1 (0.54) | PGAM1MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11872236-B2 | Pharmacological agents for treating ocular diseases | CALASIA PHARMACEUTICALS, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| US-11872236-B2 | Pharmacological agents for treating ocular diseases | CALASIA PHARMACEUTICALS, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| US-20210154213-A1 | PHARMACOLOGICAL AGENTS FOR TREATING OCULAR DISEASES | CALASIA PHARMACEUTICALS INC (US) | 2021-05-27 | — | — | US | disclosed |
| EP-2098582-B1 | FUNCTIONAL ELECTRODE AND FUNCTIONAL ELECTROCHROMIC DEVICE | RICOH CO LTD (JP) | 2017-12-06 | — | — | EP | disclosed |
| US-7830584-B2 | Organic-inorganic composite material and method for producing the same, and functional electrode and functional device | RICOH COMPANY, LTD. (JP) | 2010-11-09 | — | — | US | disclosed |
| US-7759045-B2 | Chemically amplified positive resist composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-07-20 | — | — | US | disclosed |
| EP-2098582-A1 | ORGANIC INORGANIC COMPOSITE MATERIAL, PROCESS FOR PRODUCING THE SAME, AND FUNCTIONAL ELECTRODE AND FUNCTIONAL DEVICE | Ricoh Company, Ltd. (JP) | 2009-09-09 | — | — | EP | disclosed |
| US-7489432-B2 | Electrochromic display device and display apparatus | RICOH COMPANY, LTD. (JP) | 2009-02-10 | — | — | US | disclosed |
| US-20090004601-A1 | Chemically amplified positive resist composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-01-01 | — | — | US | disclosed |
| US-20090002802-A1 | ORGANIC-INORGANIC COMPOSITE MATERIAL AND METHOD FOR PRODUCING THE SAME, AND FUNCTIONAL ELECTRODE AND FUNCTIONAL DEVICE | RICOH COMPANY, LTD. (JP) | 2009-01-01 | — | — | US | disclosed |
| US-20060215250-A1 | Electrochromic display device and display apparatus | RICOH COMPANY, LTD. (JP) | 2006-09-28 | — | — | US | disclosed |
| US-4014906-A | Process for the manufacture of anthraquinone compounds | CIBA-GEIGY CORPORATION (US) | 1977-03-29 | — | — | US | disclosed |
| US-3983145-A | Use of alpha-di(lower alkoxy) anthraquinones in the synthesis of Alizarin Saphirols | TOMS RIVER CHEMICAL CORPORATION (US) | 1976-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210154213-A1 | PHARMACOLOGICAL AGENTS FOR TREATING OCULAR DISEASES | CRYAA, CRYAB, TTR | PGAM1 2336/4885MAPT 14/4885MEN1 3695/4885 |
| US-11872236-B2 | Pharmacological agents for treating ocular diseases | CRYAA, CRYAB, TTR | PGAM1 2336/4885MAPT 14/4885MEN1 3695/4885 |
| US-20090002802-A1 | ORGANIC-INORGANIC COMPOSITE MATERIAL AND METHOD FOR PRODUCING THE SAME, AND FUNCTIONAL ELECTRODE AND FUNCTIONAL DEVICE | EPCAM, ILK, L1CAM | PGAM1 3651/4885MAPT 2202/4885MEN1 3528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.