Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | PDE4A | P27815 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29385001 | 0.78 | KDM4E (0.55) | MAPTKDM4ETHRBPDE4AMAPK1 | |
| SCHEMBL11434073 | 0.77 | L3MBTL1 (0.47) | MAPTKDM4ETHRBL3MBTL1NPC1 | |
| SCHEMBL8840880 | 0.76 | PDE4A (0.67) | MAPTKDM4ETHRBL3MBTL1NPC1 | |
| SCHEMBL30452106 | 0.75 | KDM4E (0.57) | KDM4EL3MBTL1NPC1RAB9APDE4A | |
| SCHEMBL30363200 | 0.73 | PTPRC (0.53) | MAPTKDM4ETHRBL3MBTL1NPC1 | |
| SCHEMBL5478760 | 0.72 | PTPRC (0.61) | KDM4EL3MBTL1NPC1RAB9APDE4A | |
| SCHEMBL4844181 | 0.71 | RAB9A (0.76) | MAPTKDM4ENPC1RAB9AMAPK1 | |
| SCHEMBL11434447 | 0.71 | GAK (0.48) | MAPTKDM4EL3MBTL1NPC1RAB9A | |
| SCHEMBL14003492 | 0.71 | ACHE (0.65) | MAPTKDM4ETHRBL3MBTL1NPC1 | |
| SCHEMBL8503322 | 0.71 | CA12 (0.65) | MAPTKDM4EL3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114031563-A | Cyclobutylquinoxaline compound and application thereof | 武汉科技大学 | 2022-02-11 | — | — | CN | disclosed |