Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chlorobenzene SCHEMBL28705277 | 0.83 | TSHR (0.50) | LMNANPC1MAPTALDH1A1TSHR | |
| SCHEMBL3090716 | 0.74 | LMNA (0.42) | LMNACYP2A6NPC1CA1CA2 | |
| SCHEMBL2836022 | 0.74 | MAPT (0.44) | LMNACYP2A6NPC1CA1CA2 | |
| SCHEMBL5547420 | 0.74 | LMNA (0.42) | LMNACYP2A6NPC1CA1CA2 | |
| SCHEMBL1486303 | 0.74 | NPC1 (0.43) | LMNACYP2A6NPC1CA1CA2 | |
| SCHEMBL465339 | 0.72 | — | — | |
| Benzene SCHEMBL28686547 | 0.72 | ALDH1A1 (0.45) | LMNAMAPTALDH1A1TSHRHTT | |
| Hydrochloric Acid SCHEMBL29730399 | 0.70 | ALDH1A1 (0.43) | LMNAMAPTALDH1A1TSHRPTGS2 | |
| SCHEMBL27780348 | 0.70 | ALDH1A1 (0.43) | LMNAMAPTALDH1A1TSHRPTGS2 | |
| SCHEMBL27820487 | 0.70 | ALDH1A1 (0.43) | LMNAMAPTALDH1A1TSHRPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1416933-B1 | SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEM INC (US) | 2008-01-02 | — | — | EP | claimed |