Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | UBE2N | P61088 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1917212 | 0.85 | ADORA3 (0.42) | MAPTPOLBPDE10A | |
| SCHEMBL4359050 | 0.82 | GAA (0.44) | SMN1; SMN2NPSR1NPC1RAB9AMEN1 | |
| SCHEMBL8973667 | 0.82 | POLB (0.45) | POLBPDE10AKMT2A | |
| SCHEMBL6755253 | 0.82 | PARP1 (0.54) | POLBKMT2A | |
| SCHEMBL4919557 | 0.81 | DDAH1 (0.55) | SMN1; SMN2NPSR1NPC1RAB9AMEN1 | |
| SCHEMBL6753970 | 0.81 | PARP1 (0.49) | POLB | |
| SCHEMBL6756269 | 0.81 | AAK1 (0.44) | SMN1; SMN2NPSR1POLBPDE10ANPC1 | |
| SCHEMBL6753950 | 0.81 | RAB9A (0.59) | MAPTSMN1; SMN2PDE10ANPC1RAB9A | |
| SCHEMBL6759164 | 0.80 | PARP1 (0.48) | POLB | |
| SCHEMBL6757114 | 0.80 | PARP1 (0.48) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112313274-B | Crosslinkable nitrile rubber composition and crosslinked rubber | 日本瑞翁株式会社 | 2022-08-12 | — | — | CN | disclosed |
| CN-110461892-B | Nitrile group-containing copolymer rubber | 日本瑞翁株式会社 | 2022-02-11 | — | — | CN | disclosed |