Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KRAS | P01116 | 1/20 | 0.41 |
| ▸ | CFB | P00751 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6542837 | 0.90 | GAA (0.60) | GAAEGFRERBB2KMT2AMEN1 | |
| SCHEMBL4919557 | 0.87 | DDAH1 (0.55) | GAAEGFRERBB2KMT2ANPC1 | |
| SCHEMBL8328061 | 0.86 | PKM (0.57) | GAAEGFRERBB2KMT2ANPC1 | |
| SCHEMBL5204337 | 0.85 | TDP1 (0.40) | GAAEGFRERBB2KMT2ANPC1 | |
| SCHEMBL4062828 | 0.85 | SMN1; SMN2 (0.40) | GAAEGFRERBB2KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL8323740 | 0.84 | PKM (0.59) | GAAEGFRERBB2KMT2ANPC1 | |
| SCHEMBL6759265 | 0.84 | MAPT (0.45) | GAAKMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL1917212 | 0.84 | ADORA3 (0.42) | PARP1DDAH1 | |
| SCHEMBL6757131 | 0.82 | NPC1 (0.37) | GAAEGFRERBB2KMT2ANPC1 | |
| SCHEMBL28705698 | 0.82 | HTR2A (0.44) | GAAKMT2ANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498390-B2 | Chromium complexes and their use in olefin polymerization | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2009-03-03 | — | — | US | disclosed |
| US-7498287-B2 | Chromium complexes and their use in olefin polymerization | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2009-03-03 | — | — | US | disclosed |
| US-20080071090-A1 | Chromium complexes and their use in olefin polymerization | KACKER SMITA | 2008-03-20 | — | — | US | disclosed |
| US-20080021181-A1 | Chromium complexes and their use in olefin polymerization | KACKER SMITA | 2008-01-24 | — | — | US | disclosed |
| US-7297805-B2 | Chromium complexes and their use in olefin polymerization | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2007-11-20 | — | — | US | disclosed |
| EP-1789425-A2 | CHROMIUM COMPLEXES AND THEIR USE IN OLEFIN POLYMERIZATION | ExxonMobil Research and Engineering Company (US) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006012327-A2 | CHROMIUM COMPLEXES AND THEIR USE IN OLEFIN POLYMERIZATION | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2006-02-02 | — | — | WO | disclosed |
| US-20050288464-A1 | Chromium complexes and their use in olefin polymerization | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288464-A1 | Chromium complexes and their use in olefin polymerization | CBR3, CDYL, CCRL2 | GAA 4618/4885EGFR 95/4885ERBB2 74/4885 |
| US-20080071090-A1 | Chromium complexes and their use in olefin polymerization | CBR3, CDYL, CCRL2 | GAA 4618/4885EGFR 95/4885ERBB2 74/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.