SCHEMBL28708698

SCHEMBL28708698

CCN(CC)OC(=O)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MLYCD O95822 2/20 0.33
FAAH O00519 8/20 0.32
CES2 O00748 3/20 0.31
CES1 P23141 5/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5344964 0.82 MLYCD (0.37) MLYCDFAAHCES2CES1MEN1
SCHEMBL3928482 0.79 FAAH (0.41) FAAHCES2CES1MEN1CYP1A2
SCHEMBL5004257 0.76 FAAH (0.38) MLYCDFAAHCES2CES1MEN1
SCHEMBL22042214 0.74 CHRM2 (0.31)
SCHEMBL7704563 0.74 MLYCD (0.40) MLYCD
SCHEMBL28954186 0.73 HTT (0.35) KMT2A
SCHEMBL3944363 0.72 KDM6B (0.36)
SCHEMBL8905925 0.71 PPIP5K2 (0.35) MLYCDFAAHCES2CES1MEN1
SCHEMBL7707571 0.71 ALDH1A1 (0.33)
SCHEMBL4340641 0.71 ALDH1A1 (0.38) MEN1KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114805289-B Preparation method of 1, 4-oxathia-3, 5-dialdehyde cyclohexadiene compound 昆明理工大学 2024-05-28 CN claimed
CN-116082203-A Shulin acid intermediate impurity and preparation method thereof 宁波大红鹰药业股份有限公司 2023-05-09 CN claimed
CN-114805289-A Preparation method of 1, 4-oxathia-3, 5-dialdehyde cyclohexadiene compound 昆明理工大学 2022-07-29 CN claimed
CN-114805289-B Preparation method of 1, 4-oxathia-3, 5-dialdehyde cyclohexadiene compound 昆明理工大学 2024-05-28 CN disclosed
CN-116082203-A Shulin acid intermediate impurity and preparation method thereof 宁波大红鹰药业股份有限公司 2023-05-09 CN disclosed
CN-113336654-B Preparation method of N-methyl-3- (2-methylphenoxy) amphetamine 上海医药工业研究院 2022-12-09 CN disclosed
CN-114805289-A Preparation method of 1, 4-oxathia-3, 5-dialdehyde cyclohexadiene compound 昆明理工大学 2022-07-29 CN disclosed
CN-113336654-A Preparation method of N-methyl-3- (2-methylphenoxy) amphetamine 上海医药工业研究院 2021-09-03 CN disclosed