Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 8/20 | 0.34 |
| ▸ | CES1 | P23141 | 6/20 | 0.33 |
| ▸ | CES2 | O00748 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5004257 | 0.92 | FAAH (0.38) | MLYCDFAAHCES1CES2MEN1 | |
| SCHEMBL3928482 | 0.88 | FAAH (0.41) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL28708698 | 0.82 | MLYCD (0.33) | MLYCDFAAHCES1CES2MEN1 | |
| SCHEMBL7704563 | 0.79 | MLYCD (0.40) | MLYCD | |
| SCHEMBL28444877 | 0.74 | CA12 (0.39) | CES1CES2CA12CA2CA9 | |
| SCHEMBL7024069 | 0.74 | FAAH (0.39) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL29049114 | 0.72 | CA12 (0.37) | CA12CA2CA9TSHRMAPK1 | |
| SCHEMBL5013465 | 0.72 | ALDH1A1 (0.38) | CES1HSD17B10CA12CA2CA9 | |
| SCHEMBL28778447 | 0.71 | FAAH (0.44) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL29021583 | 0.71 | FAAH (0.33) | FAAHCES1CES2MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7214699-B2 | Indazole derivatives as CRF antagonists | ROCHE PALO ALTO LLC (US) | 2007-05-08 | — | — | US | disclosed |