Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 2/20 | 0.51 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.50 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.50 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.50 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.50 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.50 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.50 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28706683 | 0.91 | FAAH (0.54) | SIGMAR1BLML3MBTL1HTTLMNA | |
| SCHEMBL28715872 | 0.88 | BLM (0.50) | BLML3MBTL1HTTLMNAFAAH | |
| SCHEMBL28716592 | 0.83 | ALDH1A1 (0.53) | BLML3MBTL1HTTLMNAFAAH | |
| SCHEMBL30525110 | 0.82 | SIGMAR1 (0.49) | SIGMAR1L3MBTL1LMNAFAAHPRKAB2 | |
| SCHEMBL30525111 | 0.74 | FAAH (0.48) | SIGMAR1HTTLMNAFAAHALDH1A1 | |
| SCHEMBL30064690 | 0.74 | SIGMAR1 (0.66) | SIGMAR1L3MBTL1FAAHPRKAB2PRKAG1 | |
| SCHEMBL27629355 | 0.71 | SIGMAR1 (0.68) | SIGMAR1L3MBTL1FAAHPRKAB2PRKAG1 | |
| SCHEMBL6706057 | 0.71 | MCHR1 (0.59) | ALDH1A1MAPT | |
| SCHEMBL15687847 | 0.70 | HPD (0.52) | LMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL15842125 | 0.70 | RORC (0.71) | SIGMAR1L3MBTL1LMNAPRKAB2PRKAG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461640-A | LPAR1 inhibitor, medical application and preparation method thereof | 中央民族大学 | 2021-10-01 | — | — | CN | claimed |
| CN-113461640-A | LPAR1 inhibitor, medical application and preparation method thereof | 中央民族大学 | 2021-10-01 | — | — | CN | disclosed |