Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MLYCD | O95822 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27616693 | 0.82 | CTSL (0.60) | CTSLGAARAB9AMAPTTDP1 | |
| SCHEMBL19485398 | 0.82 | MAPT (0.59) | CTSLGAARAB9AMAPTTDP1 | |
| SCHEMBL20838245 | 0.81 | CTSL (0.60) | CTSLGAARAB9AMAPTTDP1 | |
| SCHEMBL9237730 | 0.81 | RAB9A (0.61) | CTSLGAARAB9AMAPTTDP1 | |
| SCHEMBL9237734 | 0.81 | RAB9A (0.61) | CTSLGAARAB9AMAPTTDP1 | |
| SCHEMBL19437160 | 0.81 | CTSL (0.60) | CTSLGAARAB9AMAPTTDP1 | |
| SCHEMBL27808602 | 0.80 | CTSL (0.65) | CTSLGAARAB9AALDH1A1LMNA | |
| SCHEMBL27808603 | 0.80 | CTSL (0.65) | CTSLGAARAB9AALDH1A1LMNA | |
| SCHEMBL31206887 | 0.78 | GAA (0.76) | CTSLGAARAB9APOLBALDH1A1 | |
| SCHEMBL2461492 | 0.78 | GAA (0.76) | CTSLGAARAB9APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153635-B | Neuropeptide S receptor (NPSR) agonists | 研究三角协会 | 2022-04-08 | — | — | CN | disclosed |