Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 7/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2096480 | 0.81 | PTPN1 (0.43) | PTPN1GSK3BDGAT1HPGDS | |
| SCHEMBL13181120 | 0.80 | ALDH1A1 (0.41) | ALDH1A1MAPTKEAP1KDM4EHPGD | |
| SCHEMBL8129297 | 0.76 | SLC9A1 (0.41) | PTPN1ALDH1A1GSK3BHPGD | |
| SCHEMBL3921010 | 0.76 | POLB (0.47) | PTPN1MAPTGSK3BHPGD | |
| SCHEMBL222733 | 0.74 | KEAP1 (0.57) | PTPN1ALDH1A1MAPTKEAP1KDM4E | |
| SCHEMBL1203088 | 0.74 | DGAT1 (0.45) | ALDH1A1MAPTKEAP1DGAT1HDAC1 | |
| SCHEMBL16914072 | 0.73 | GSK3B (0.42) | PTPN1GSK3B | |
| SCHEMBL31726717 | 0.72 | TSHR (0.40) | ALDH1A1MAPTKEAP1HDAC1HDAC6 | |
| SCHEMBL1721699 | 0.72 | TSHR (0.40) | ALDH1A1MAPTKEAP1HDAC1HDAC6 | |
| SCHEMBL1194251 | 0.72 | GSK3B (0.38) | PTPN1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527358-A | Synthesis process of S- (-) -nadifloxacin chiral intermediate | 湖南中威制药有限公司 | 2021-10-22 | — | — | CN | disclosed |