Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.40 |
| ▸ | RXRG | P48443 | 3/20 | 0.40 |
| ▸ | RXRB | P28702 | 2/20 | 0.40 |
| ▸ | FLT3 | P36888 | 3/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | QPCT | Q16769 | 3/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2267261 | 0.74 | KIF11 (0.57) | RXRARXRGRXRBKIF11 | |
| SCHEMBL7594667 | 0.73 | RXRA (0.54) | RXRARXRGRXRBMMP3KIF11 | |
| SCHEMBL28730706 | 0.73 | TNF (0.38) | RXRARXRGRXRBFLT3MMP3 | |
| SCHEMBL196175 | 0.73 | MMP3 (0.50) | RXRARXRGRXRBFLT3MMP3 | |
| SCHEMBL23137321 | 0.73 | MMP3 (0.50) | RXRARXRGRXRBFLT3MMP3 | |
| SCHEMBL30439382 | 0.71 | MMP3 (0.50) | RXRARXRGRXRBFLT3MMP3 | |
| SCHEMBL21774188 | 0.71 | PDPK1 (0.44) | RXRARXRGRXRBFLT3PDPK1 | |
| SCHEMBL21021174 | 0.70 | MAOB (0.59) | RXRARXRGRXRBFLT3MMP3 | |
| SCHEMBL21774316 | 0.69 | KIF11 (0.50) | PDE3BPDE3AQPCTKIF11 | |
| SCHEMBL2773349 | 0.68 | MAOB (0.47) | RXRARXRGRXRBFLT3MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113613652-B | Benzimidazole compounds and their use in the treatment of alzheimer's disease or huntington's disease | 台湾卫生研究院 | 2022-08-23 | — | — | CN | disclosed |
| CN-113613652-A | Benzimidazole compounds and their use for treating alzheimer's disease or huntington's disease | 台湾卫生研究院 | 2021-11-05 | — | — | CN | disclosed |