SCHEMBL287360

SCHEMBL287360

NCCCC[C@H](NC(=O)C(F)(F)F)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 1/20 0.57
▸ SLC6A5 Q9Y345 1/20 0.45
▸ CA1 P00915 2/20 0.45
▸ CA2 P00918 2/20 0.45
▸ CA12 O43570 1/20 0.45
▸ CA9 Q16790 1/20 0.45
▸ GSR P00390 1/20 0.44
▸ RNPEP Q9H4A4 1/20 0.43
▸ CPB2 Q96IY4 9/20 0.41
▸ MMP2 P08253 1/20 0.40
▸ MMP9 P14780 1/20 0.40
▸ SLC15A2 Q16348 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL287361 1.00 FOLH1 (0.57) FOLH1SLC6A5CA1CA2CA12
SCHEMBL30915497 1.00 FOLH1 (0.57) FOLH1SLC6A5CA1CA2CA12
SCHEMBL28151343 0.98 FOLH1 (0.55) FOLH1SLC6A5CA1CA2CA12
SCHEMBL28151347 0.98 FOLH1 (0.55) FOLH1SLC6A5CA1CA2CA12
SCHEMBL28151408 0.98 FOLH1 (0.55) FOLH1SLC6A5CA1CA2CA12
SCHEMBL29720838 0.98 FOLH1 (0.55) FOLH1SLC6A5CA1CA2CA12
SCHEMBL28151407 0.98 FOLH1 (0.55) FOLH1SLC6A5CA1CA2CA12
SCHEMBL6153373 0.95 FOLH1 (0.50) FOLH1SLC6A5CA1CA2CA12
SCHEMBL6153374 0.95 FOLH1 (0.50) FOLH1SLC6A5CA1CA2CA12
SCHEMBL6153376 0.95 FOLH1 (0.50) FOLH1SLC6A5CA1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 650 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4211146-B1 SYNTHETIC CYCLIC PEPTIDE MIMETICS UNIV BAR ILAN (IL) 2026-05-20 — — EP claimed
US-12616760-B2 Synthetic cyclic peptide mimetics BAR ILAN UNIVERSITY (IL) 2026-05-05 — — US claimed
US-20260042739-A1 Formation of N-Protected 3,6-bis-(4-aminoalkyl)-2,5,diketopiperazine MANNKIND CORP (US) 2026-02-12 — — US claimed
US-20250208137-A1 COMPOUNDS FOR THE DETECTION AND INHIBITION OF COAGULATION PROTEASES CAMBRIDGE ENTERPRISE LIMITED (GB) 2025-06-26 — — US claimed
US-20250163003-A1 Formation of N-Protected 3,6-bis-(4-aminoalkyl)-2,5,diketopiperazine WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2025-05-22 — — US claimed
CN-119591553-A Diamino diketone application of piperazine compound 上海昊海生物科技股份有限公司 2025-03-11 — — CN claimed
EP-4493273-A1 COMPOUNDS FOR THE DETECTION AND INHIBITION OF COAGULATION PROTEASES Politechnika Wroclawska (PL) 2025-01-22 — — EP claimed
CN-118406439-B Chemical mechanical polishing composition and application thereof in tungsten chemical mechanical polishing 万华化学集团电子材料有限公司 2024-10-18 — — CN claimed
CN-118108617-B Production process of trifluoroacetyl lysine 山东极地医药科技有限公司 2024-10-15 — — CN claimed
US-20240316225-A1 SYNTHETIC CYCLIC PEPTIDE MIMETICS BAR ILAN UNIVERSITY (IL) 2024-09-26 — — US claimed
US-20020183551-A1 Process for the preparation of N-carboxyanhydrides ISOCHEM (FR) 2002-12-05 — — US claimed
EP-1262480-A1 Process for the preparation of N-carboxyanhydrides of amino acids ISOCHEM (FR) 2002-12-04 — — EP claimed
US-6479665-B2 REACTING ALPHA-, BETA- OR GAMMA- AMINO ACID OR OF ONE OF ITS SALTS WITH PHOSGENE, DIPHOSGENE AND/OR TRIPHOSGENE IN A SOLVENT MEDIUM, IN PRESENCE OF UNSATURATED ORGANIC COMPOUND WHICH HAS ONE OR MORE ETHYLENIC DOUBLE BONDS ISOCHEM (FR) 2002-11-12 — — US claimed
US-20020082431-A1 Process for the preparation of N-carboxyanhydrides ISOCHEM (FR) 2002-06-27 — — US claimed
EP-1201659-A1 Process for the preparation of N-carboxyanhydrides ISOCHEM (FR) 2002-05-02 — — EP claimed
EP-0517788-A1 19 F LABELLED COMPOUNDS AS NMR IMAGING AND SPECTROSCOPY AGENTS. UNIV TEXAS (US) 1992-12-16 — — EP claimed
WO-1991012824-A2 19F LABELLED COMPOUNDS AS NMR IMAGING AND SPECTROSCOPY AGENTS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1991-09-05 — — WO claimed
EP-0213996-B1 RAMIFIED POLYMERS BASED ON LIPOPEPTIDES FORMING THERMOTROPIC AND LYOTROPIC LIQUID CRYSTALS, THEIR USE AND CORRESPONDING MONOMERS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1989-09-06 — — EP claimed
EP-0239062-A2 N2-(1-carboxy-3-oxo-3-phenylpropyl)-L-Lysine compounds and their derivatives KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-09-30 — — EP claimed
EP-0213996-A1 Ramified polymers based on lipopeptides forming thermotropic and lyotropic liquid crystals, their use and corresponding monomers CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1987-03-11 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020183551-A1 Process for the preparation of N-carboxyanhydrides NPEPPS, DDOST, DNPEP FOLH1 279/4885SLC6A5 690/4885CA1 2401/4885
US-20260042739-A1 Formation of N-Protected 3,6-bis-(4-aminoalkyl)-2,5,diketopiperazine ACMSD, DNPEP, PGM2 FOLH1 1264/4885SLC6A5 76/4885CA1 428/4885
US-20250163003-A1 Formation of N-Protected 3,6-bis-(4-aminoalkyl)-2,5,diketopiperazine PGM2, DNPEP, NPEPPS FOLH1 1006/4885SLC6A5 355/4885CA1 243/4885
US-12616760-B2 Synthetic cyclic peptide mimetics TPX2, IAPP, HAX1 FOLH1 1510/4885SLC6A5 2249/4885CA1 208/4885
US-20240316225-A1 SYNTHETIC CYCLIC PEPTIDE MIMETICS IAPP, QPCTL, DNPEP FOLH1 701/4885SLC6A5 3038/4885CA1 304/4885
US-20250208137-A1 COMPOUNDS FOR THE DETECTION AND INHIBITION OF COAGULATION PROTEASES F11, F2, F12 FOLH1 1307/4885SLC6A5 4823/4885CA1 674/4885
US-20020082431-A1 Process for the preparation of N-carboxyanhydrides NPEPPS, CPN1, DDOST FOLH1 431/4885SLC6A5 1676/4885CA1 3068/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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